Interactor 1: RAP2A (P10114)
Ras-related protein Rap-2a (EC 3.6.5.2) (RbBP-30)
Gene: RAP2A
Interactor 2: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DIL~Ras, PDZ~Ras, RA~Ras |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030336 - negative regulation of cell migration |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
