HitPredict

Interactor 1: MYCL (P12524)
Protein L-Myc (Class E basic helix-loop-helix protein 38) (bHLHe38) (Protein L-Myc-1) (V-myc myelocytomatosis viral oncogene homolog)
Gene: MYCL

Interactor 2: EPC1 (Q9H2F5)
Enhancer of polycomb homolog 1
Gene: EPC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	29028833, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 364 Hs			1 836
+	Hs
		347870 MYC_HUMAN (1-362): 1e-76: 245: 29.75		EPC1_HUMAN (1-836): 0: 1049: 100.00
+	Hs
		519717 MYCL_HUMAN (1-364): 4.25e-117: 345: 100.00		EPC2_HUMAN (1-836): 0: 925: 52.91
+	Mm
		348437 MYC_MOUSE (1-362): 4.56e-78: 248: 29.98		EPC1_MOUSE (1-836): 0: 1020: 87.56
+	Mm
		348436 MYC_MOUSE (1-362): 4.56e-78: 248: 29.98		EPC2_MOUSE (1-836): 0: 942: 52.43
+	Hs
		346955 MYC_HUMAN (1-362): 1e-76: 245: 29.75		EPC2_HUMAN (1-836): 0: 925: 52.91
+	Hs
		898193 MAX_HUMAN (278-362): 3.89e-21: 90.8: 34.12		EPC1_HUMAN (1-836): 0: 1049: 100.00
+	Hs
		898135 MAX_HUMAN (278-362): 3.89e-21: 90.8: 34.12		EPC2_HUMAN (1-836): 0: 925: 52.91