Interactor 1: HLAC (P10321)
HLA class I histocompatibility antigen, C alpha chain (HLA-C) (HLA-Cw) (Human leukocyte antigen C)
Gene: HLA-C

Interactor 2: KI2L2 (P43627)
Killer cell immunoglobulin-like receptor 2DL2 (CD158 antigen-like family member B1) (Natural killer-associated transcript 6) (NKAT-6) (p58 natural killer cell receptor clone CL-43) (p58 NK receptor CL-43) (CD antigen CD158b1)
Gene: KIR2DL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 10850706, 18322206, 24018270
Identification Methods x-ray crystallography, affinity chromatography technology, surface plasmon resonance
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~ig, MHC_I~ig
Common GO terms GO:0005886 - plasma membrane
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 366
Hs

1 348
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Service provided by Combinatics, Japan

Last updated: 11Aug2025