HitPredict

Interactor 1: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1

Interactor 2: PTN1 (P18031)
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
Gene: PTPN1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25468996, 17087658
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 882 Hs			1 435
+	Hs
		521898 CADH1_HUMAN (1-882): 0: 836: 100.00		PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44
+	Hs
		521907 CADH1_HUMAN (1-882): 0: 836: 100.00		PTPRS_HUMAN (1-278): 3.66e-109: 355: 30.74
+	Hs
		521727 CADH1_HUMAN (1-882): 0: 836: 100.00		PTPRD_HUMAN (1-278): 8.51e-109: 354: 31.45
+	Hs
		489891 CADH1_HUMAN (1-882): 0: 836: 100.00		PTPRF_HUMAN (19-278): 2.99e-105: 344: 30.94
+	Hs
		573632 CAD13_HUMAN (8-701): 0: 633: 36.20		PTN1_HUMAN (1-435): 0: 539: 100.00
+	Hs
		580200 CADH2_HUMAN (28-881): 0: 769: 45.86		PTPRB_HUMAN (2-311): 4.08e-124: 398: 34.39
+	Hs
		580229 CADH2_HUMAN (28-881): 0: 769: 45.86		PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44
+	Hs
		580226 CADH2_HUMAN (28-881): 0: 769: 45.86		PTN12_HUMAN (24-314): 1e-122: 376: 33.55
+	Hs
		576981 CADH2_HUMAN (28-881): 0: 769: 45.86		PTPRA_HUMAN (12-278): 9.1e-105: 330: 31.62
+	Hs
		521743 CADH1_HUMAN (1-882): 0: 836: 100.00		PTPRM_HUMAN (7-281): 2.32e-63: 223: 26.48
+	Hs
		441173 CADH2_HUMAN (28-881): 0: 769: 45.86		PTPRC_HUMAN (16-337): 3.28e-77: 263: 22.95
+	Mm
		454946 CADH1_MOUSE (1-882): 0: 799: 81.45		PTPRM_MOUSE (7-281): 1.28e-63: 224: 26.48
+	Hs
		616974 DSC3_HUMAN (2-874): 0: 655: 27.92		PTPRD_HUMAN (1-278): 8.51e-109: 354: 31.45
+	Hs
		580235 CADH2_HUMAN (28-881): 0: 769: 45.86		PTPRK_HUMAN (6-279): 1.27e-61: 218: 25.18
+	Hs
		580238 CADH2_HUMAN (28-881): 0: 769: 45.86		PTPRO_HUMAN (20-274): 4.19e-48: 178: 38.31
+	Hs
		521728 CADH1_HUMAN (1-882): 0: 836: 100.00		PTPRG_HUMAN (342-435): 1.43e-21: 99.7: 13.46
+	Hs
		580201 CADH2_HUMAN (28-881): 0: 769: 45.86		PTPRG_HUMAN (342-435): 1.43e-21: 99.7: 13.46
+	Hs
		580269 CADH2_HUMAN (28-881): 0: 769: 45.86		PTN22_HUMAN (297-430): 8.46e-19: 91.2: 13.10
+	Hs
		580204 CADH2_HUMAN (28-881): 0: 769: 45.86		PTN6_HUMAN (342-432): 1.75e-12: 71.2: 10.48
+	Hs
		490028 PCDBG_HUMAN (376-868): 1.94e-73: 258: 16.96		PTPRF_HUMAN (19-278): 2.99e-105: 344: 30.94