HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: PSA2 (P23639)
Proteasome subunit alpha type-2 (Macropain subunit Y7) (Multicatalytic endopeptidase complex subunit Y7) (Proteasome component Y7) (Proteinase YSCE subunit 7)
Gene: PRE8

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	32868373, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 250
+	Sc
		523114 HSP71_YEAST (1-639): 0: 968: 97.04		PSA2_YEAST (1-250): 2.36e-95: 281: 100.00
+	Dm
		538228 HSP7D_DROME (2-607): 0: 932: 75.53		PSA2_DROME (2-250): 2.45e-105: 306: 53.41
+	Hs
		536556 HSP7C_HUMAN (2-639): 0: 945: 74.34		PSA5_HUMAN (3-250): 4.69e-92: 272: 30.04
+	Hs
		536535 HSP7C_HUMAN (2-639): 0: 945: 74.34		PSA4_HUMAN (1-247): 3.04e-91: 271: 34.40
+	Hs
		536863 HSP7C_HUMAN (2-639): 0: 945: 74.34		PSA6_HUMAN (2-250): 2.62e-91: 270: 32.54
+	Hs
		165245 HSP7C_HUMAN (2-639): 0: 945: 74.34		PSA7_HUMAN (1-248): 5.95e-90: 267: 32.00
+	Hs
		536533 HSP7C_HUMAN (2-639): 0: 945: 74.34		PSA2_HUMAN (1-250): 4.63e-90: 267: 56.97
+	Sc
		523113 HSP71_YEAST (1-639): 0: 968: 97.04		PSA3_YEAST (4-214): 4.64e-42: 145: 37.09