HitPredict

Interactor 1: CLCB (P09497)
Clathrin light chain B (Lcb)
Gene: CLTB

Interactor 2: AP2M1 (Q96CW1)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport GO:0045334 - clathrin-coated endocytic vesicle GO:0072583 - clathrin-dependent endocytosis
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 229 Hs			1 435
+	Hs
		451529 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		451547 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Hs
		451725 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Hs
		451515 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		STON2_HUMAN (146-433): 1.58e-62: 219: 22.85
+	Hs
		451713 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		STON2_HUMAN (146-433): 1.58e-62: 219: 22.85