Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR
Interactor 2: TAP2 (Q03519)
Antigen peptide transporter 2 (APT2) (EC 7.4.2.14) (ATP-binding cassette sub-family B member 3) (Peptide supply factor 2) (Peptide transporter PSF2) (PSF-2) (Peptide transporter TAP2) (Peptide transporter involved in antigen processing 2) (Really interesting new gene 11 protein) (RING11)
Gene: TAP2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26618866 |
| Identification Methods | affinity chromatography technology, anti bait coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ABC_membrane~ABC_membrane, ABC_membrane~ABC_tran, ABC_tran~ABC_tran, ABC_membrane~CFTR_R, ABC_tran~CFTR_R |
| Common GO terms | GO:0005524 - ATP binding GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane GO:0016887 - ATP hydrolysis activity GO:0055085 - transmembrane transport |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
