HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: K1C24 (Q2M2I5)
Keratin, type I cytoskeletal 24 (Cytokeratin-24) (CK-24) (Keratin-24) (K24) (Type I keratin-24)
Gene: KRT24

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31324722
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1480 Hs			1 525
+	Hs
		529011 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K1C17_HUMAN (133-517): 4.06e-147: 430: 55.33
+	Hs
		529614 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K1C12_HUMAN (131-522): 6.15e-146: 430: 57.91
+	Hs
		528449 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K1C13_HUMAN (129-468): 1.16e-145: 427: 59.71
+	Hs
		528448 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K1C10_HUMAN (135-450): 1.02e-141: 422: 68.35
+	Hs
		359298 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K1C14_HUMAN (104-515): 3.58e-118: 358: 51.70
+	Hs
		444303 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K1C19_HUMAN (134-452): 2.1e-119: 358: 58.62
+	Hs
		528674 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K1C9_HUMAN (135-463): 1.36e-103: 325: 52.58
+	Hs
		529780 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KRT84_HUMAN (1-456): 7.62e-98: 309: 24.64
+	Hs
		529151 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K1H1_HUMAN (134-452): 2.14e-99: 308: 48.59
+	Hs
		528963 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KRT85_HUMAN (1-456): 1.58e-91: 290: 26.42
+	Hs
		529119 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KRT81_HUMAN (16-456): 1e-88: 283: 25.51
+	Hs
		213928 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KRT86_HUMAN (19-456): 1.01e-86: 277: 25.46
+	Hs
		318772 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C75_HUMAN (2-459): 1.43e-85: 276: 24.46
+	Hs
		529503 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KRT35_HUMAN (46-456): 9.07e-76: 248: 43.34
+	Hs
		529130 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C72_HUMAN (31-459): 1.08e-72: 241: 22.88
+	Hs
		529332 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C74_HUMAN (3-459): 3.75e-71: 238: 21.79
+	Hs
		528450 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C5_HUMAN (2-459): 6.74e-70: 236: 23.97
+	Hs
		380440 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C6B_HUMAN (2-475): 1.06e-69: 235: 23.68
+	Hs
		528760 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C6C_HUMAN (2-475): 1.57e-69: 234: 23.89
+	Hs
		359458 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C6A_HUMAN (106-475): 1.54e-67: 229: 23.93