HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: DBNL (Q9UJU6)
Drebrin-like protein (Cervical SH3P7) (Cervical mucin-associated protein) (Drebrin-F) (HPK1-interacting protein of 55 kDa) (HIP-55) (SH3 domain-containing protein 7)
Gene: DBNL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	26618866, 31324722
Identification Methods	affinity chromatography technology, cross-linking study, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005769 - early endosome GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 430
+	Hs
		529184 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DREB_HUMAN (3-379): 1.4e-59: 207: 29.19
+	Hs
		528466 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HCLS1_HUMAN (122-430): 5.78e-36: 140: 23.99
+	Hs
		529052 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYO1E_HUMAN (147-429): 3.45e-33: 134: 14.84
+	Hs
		529105 CFTR_HUMAN (1-1480): 0: 1031: 100.00		SRC8_HUMAN (120-430): 9.82e-34: 134: 25.71
+	Hs
		235466 CFTR_HUMAN (1-1480): 0: 1031: 100.00		VINEX_HUMAN (283-429): 1.82e-14: 77.4: 18.67
+	Hs
		529127 CFTR_HUMAN (1-1480): 0: 1031: 100.00		LASP1_HUMAN (246-429): 2.85e-15: 77.3: 24.24