HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: MTCL3 (Q5TF21)
Microtubule cross-linking factor 3
Gene: MTCL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010506 - regulation of autophagy
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 947
+	Hs
		529006 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		DESP_HUMAN (293-825): 4.71e-21: 102: 12.07
+	Hs
		530549 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MYH2_HUMAN (221-882): 2.57e-16: 86.5: 10.78
+	Hs
		529710 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		KIF5A_HUMAN (347-738): 3e-16: 85.8: 19.04
+	Hs
		116933 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		J3KNA1_HUMAN (347-738): 2.17e-15: 83.1: 19.04
+	Hs
		270762 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		ROCK2_HUMAN (347-773): 5.73e-15: 81.9: 22.08
+	Hs
		529216 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MYH9_HUMAN (506-908): 4.98e-14: 79: 11.49
+	Hs
		530422 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MYO5C_HUMAN (686-937): 8.03e-12: 71.6: 9.52
+	Hs
		590235 MUC1_HUMAN (39-730): 2.41e-41: 165: 11.50		MUC1_HUMAN (17-302): 3.21e-20: 99: 11.22
+	Hs
		158047 PCLO_HUMAN (21-757): 4.9e-30: 130: 10.00		CTRO_HUMAN (395-915): 6.47e-24: 111: 12.64
+	Hs
		551856 MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48		CO6A2_HUMAN (3-180): 2.06e-26: 118: 14.42
+	Hs
		157378 MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48		CTRO_HUMAN (395-915): 6.47e-24: 111: 12.64
+	Hs
		551605 NFH_HUMAN (113-708): 1.12e-25: 115: 10.96		MYH9_HUMAN (506-908): 4.98e-14: 79: 11.49
+	Hs
		587777 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		DESP_HUMAN (293-825): 4.71e-21: 102: 12.07
+	Dm
		1039713 CPN_DROME (353-756): 7.79e-12: 70.8: 13.55		Q9VTY8_DROME (339-859): 3.2e-15: 83.1: 18.13
+	Dm
		122290 CPN_DROME (353-756): 7.79e-12: 70.8: 13.55		M9PI41_DROME (339-859): 3.04e-15: 83.1: 18.13