HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: IF2B2 (Q9Y6M1)
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)
Gene: IGF2BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	26618866, 29924966
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 599
+	Hs
		128010 CFTR_HUMAN (1-1480): 0: 1031: 100.00		IF2B3_HUMAN (2-599): 4.89e-134: 405: 62.36
+	Hs
		528850 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PCBP3_HUMAN (385-597): 7.22e-39: 148: 24.31
+	Hs
		529153 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PCBP2_HUMAN (422-597): 7.25e-36: 140: 26.92
+	Hs
		528886 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HNRPK_HUMAN (386-596): 5.84e-18: 88.9: 17.09
+	Hs
		528980 CFTR_HUMAN (1-1480): 0: 1031: 100.00		VIGLN_HUMAN (444-585): 4.33e-12: 71.5: 19.01
+	Hs
		529509 CFTR_HUMAN (1-1480): 0: 1031: 100.00		FUBP2_HUMAN (414-584): 1.07e-10: 66.6: 28.73
+	Hs
		529152 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PCBP1_HUMAN (422-530): 8.21e-11: 65.8: 25.69