HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1025
+	Hs
		529962 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51
+	Hs
		529217 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MYH10_HUMAN (242-1024): 1.66e-21: 103: 8.45
+	Hs
		270762 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		ROCK2_HUMAN (446-1018): 5.24e-17: 88.7: 11.81
+	Hs
		530549 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MYH2_HUMAN (125-1012): 6.38e-17: 88.6: 10.27
+	Hs
		529216 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35
+	Hs
		529830 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PLEC_HUMAN (499-978): 3.11e-11: 70.1: 14.96
+	Hs
		530018 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MYH14_HUMAN (595-972): 3.71e-09: 63.1: 14.89
+	Rn
		620102 TAU_RAT (1-758): 3.21e-76: 263: 72.11		MYH10_RAT (540-1024): 2.28e-15: 83.6: 10.20
+	Rn
		98796 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		MYH10_RAT (540-1024): 2.28e-15: 83.6: 10.20
+	Hs
		96000 E7EVA0_HUMAN (214-725): 3.71e-32: 137: 25.82		PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51
+	Hs
		215931 SYNJ1_HUMAN (173-636): 8.49e-14: 77.6: 14.41		PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51
+	Hs
		698371 MAP4_HUMAN (22-721): 3.01e-10: 66.2: 9.24		PKHA5_HUMAN (318-1019): 2.96e-36: 151: 13.24
+	Hs
		551605 NFH_HUMAN (113-708): 1.12e-25: 115: 10.96		MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35
+	Hs
		536342 MTAP2_HUMAN (16-758): 7.48e-30: 129: 23.42		PLEC_HUMAN (499-978): 3.11e-11: 70.1: 14.96
+	Hs
		1129640 MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48		MYH14_HUMAN (595-972): 3.71e-09: 63.1: 14.89
+	Hs
		1143196 KMT2C_HUMAN (228-752): 7.28e-09: 62: 7.94		PLEC_HUMAN (499-978): 3.11e-11: 70.1: 14.96