HitPredict

Interactor 1: MTAP2 (P11137)
Microtubule-associated protein 2 (MAP-2)
Gene: MAP2

Interactor 2: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	3027087
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002162 - dystroglycan binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030425 - dendrite
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1827 Hs			1 4684
+	Hs
		529830 TAU_HUMAN (1069-1827): 2.86e-51: 197: 24.46		PLEC_HUMAN (1-4684): 0: 1793: 100.00
+	Hs
		1008619 MAP1A_HUMAN (29-1821): 4.19e-43: 175: 9.98		PLEC_HUMAN (1-4684): 0: 1793: 100.00
+	Hs
		1143307 SRRM2_HUMAN (9-1646): 2.33e-19: 97.8: 8.08		PLEC_HUMAN (1-4684): 0: 1793: 100.00
+	Hs
		536308 MTAP2_HUMAN (1-1827): 0: 645: 100.00		ACTN1_HUMAN (153-894): 1.99e-116: 396: 23.90
+	Hs
		528966 TAU_HUMAN (1069-1827): 2.86e-51: 197: 24.46		ACTN1_HUMAN (153-894): 1.99e-116: 396: 23.90
+	Hs
		1061541 TITIN_HUMAN (53-1766): 2.4e-29: 131: 8.45		ACTN3_HUMAN (166-891): 1.55e-120: 408: 25.86
+	Hs
		555729 TITIN_HUMAN (53-1766): 2.4e-29: 131: 8.45		ACTN1_HUMAN (153-894): 1.99e-116: 396: 23.90
+	Hs
		555743 CIC_HUMAN (29-1680): 1.08e-16: 89.3: 8.78		ACTN1_HUMAN (153-894): 1.99e-116: 396: 23.90
+	Hs
		529644 TAU_HUMAN (1069-1827): 2.86e-51: 197: 24.46		SPTB2_HUMAN (1005-2737): 3.24e-30: 135: 9.83
+	Rn
		620105 TAU_RAT (1091-1827): 3.98e-59: 221: 25.10		SPTN2_RAT (1516-3107): 2.19e-19: 99.7: 11.31
+	Rn
		98798 F1LST4_RAT (1091-1826): 1.21e-58: 220: 25.00		SPTN2_RAT (1516-3107): 2.19e-19: 99.7: 11.31
+	Hs
		174695 TAU_HUMAN (1069-1827): 2.86e-51: 197: 24.46		SPTN2_HUMAN (1390-3107): 3.29e-22: 108: 12.11
+	Hs
		530366 TAU_HUMAN (1069-1827): 2.86e-51: 197: 24.46		SPTN4_HUMAN (1380-3073): 2.14e-16: 89.7: 11.41
+	Hs
		529006 TAU_HUMAN (1069-1827): 2.86e-51: 197: 24.46		DESP_HUMAN (404-1000): 1.7e-12: 76.9: 9.56
+	Hs
		1028910 SRRM2_HUMAN (9-1646): 2.33e-19: 97.8: 8.08		SPTB2_HUMAN (1005-2737): 3.24e-30: 135: 9.83
+	Hs
		945879 SRRM2_HUMAN (9-1646): 2.33e-19: 97.8: 8.08		EPIPL_HUMAN (4390-4637): 2.39e-28: 129: 29.25
+	Hs
		945843 CIC_HUMAN (29-1680): 1.08e-16: 89.3: 8.78		EPIPL_HUMAN (4390-4637): 2.39e-28: 129: 29.25
+	Hs
		587751 TITIN_HUMAN (53-1766): 2.4e-29: 131: 8.45		DESP_HUMAN (404-1000): 1.7e-12: 76.9: 9.56
+	Hs
		854004 KI67_HUMAN (62-1729): 5.6e-24: 113: 10.08		DYST_HUMAN (3439-3682): 1.46e-13: 80.3: 20.90
+	Hs
		587777 CIC_HUMAN (29-1680): 1.08e-16: 89.3: 8.78		DESP_HUMAN (404-1000): 1.7e-12: 76.9: 9.56