HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: BD1L1 (Q8NFC6)
Biorientation of chromosomes in cell division protein 1-like 1
Gene: BOD1L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36634849, 26269332
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006974 - DNA damage response
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 3051
+	Hs
		1129658 MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48		BD1L1_HUMAN (1-3051): 0: 2164: 100.00
+	Hs
		161492 KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76		BD1L1_HUMAN (1-3051): 0: 2164: 100.00
+	Hs
		1338259 KMT2C_HUMAN (228-752): 7.28e-09: 62: 7.94		BD1L1_HUMAN (1-3051): 0: 2164: 100.00
+	Hs
		529006 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		DESP_HUMAN (68-895): 2.51e-37: 158: 14.32
+	Rn
		620102 TAU_RAT (1-758): 3.21e-76: 263: 72.11		MYH10_RAT (374-1460): 3.37e-43: 177: 9.91
+	Rn
		98796 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		MYH10_RAT (374-1460): 3.37e-43: 177: 9.91
+	Hs
		529216 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MYH9_HUMAN (45-877): 2.52e-31: 138: 11.52
+	Hs
		530549 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MYH2_HUMAN (21-921): 4.21e-30: 133: 8.76
+	Hs
		67527 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MYH7B_HUMAN (18-920): 4.42e-28: 127: 8.50
+	Hs
		529217 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MYH10_HUMAN (741-1629): 2e-24: 115: 9.17
+	Hs
		529988 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		WDR87_HUMAN (235-1099): 2.55e-22: 108: 15.83
+	Hs
		529830 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PLEC_HUMAN (449-1746): 4.94e-19: 97.8: 8.43
+	Hs
		530150 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MY18A_HUMAN (545-1152): 5e-12: 74.5: 15.09
+	Hs
		551605 NFH_HUMAN (113-708): 1.12e-25: 115: 10.96		MYH9_HUMAN (45-877): 2.52e-31: 138: 11.52
+	Hs
		536342 MTAP2_HUMAN (16-758): 7.48e-30: 129: 23.42		PLEC_HUMAN (449-1746): 4.94e-19: 97.8: 8.43
+	Hs
		587777 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		DESP_HUMAN (68-895): 2.51e-37: 158: 14.32
+	Hs
		1143196 KMT2C_HUMAN (228-752): 7.28e-09: 62: 7.94		PLEC_HUMAN (449-1746): 4.94e-19: 97.8: 8.43
+	Dm
		1039713 CPN_DROME (353-756): 7.79e-12: 70.8: 13.55		Q9VTY8_DROME (197-1008): 2.57e-14: 82.2: 15.81
+	Dm
		122290 CPN_DROME (353-756): 7.79e-12: 70.8: 13.55		M9PI41_DROME (197-1008): 2.23e-14: 82.2: 15.81