HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	27383765
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:1900034 - regulation of cellular response to heat
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 2442
+	Hs
		1129671 MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48		CBP_HUMAN (1-2442): 0: 1096: 100.00
+	Hs
		1253860 SRCAP_HUMAN (168-756): 9.46e-12: 71.2: 11.72		CBP_HUMAN (1-2442): 0: 1096: 100.00
+	Hs
		1256336 Q6ZTM8_HUMAN (353-756): 2.04e-11: 69.3: 8.51		CBP_HUMAN (1-2442): 0: 1096: 100.00
+	Hs
		530031 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PB1_HUMAN (1040-1195): 4.73e-12: 74.4: 19.87
+	Hs
		215898 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		SYNJ1_HUMAN (2094-2436): 6.84e-09: 63.7: 10.53
+	Hs
		529703 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		EP300_HUMAN (1789-2434): 7.34e-09: 63.6: 13.61
+	Hs
		590235 MUC1_HUMAN (39-730): 2.41e-41: 165: 11.50		MUC1_HUMAN (1841-2425): 1.24e-24: 115: 13.64
+	Hs
		1129788 MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48		TRI33_HUMAN (614-1207): 1.09e-36: 154: 13.64
+	Hs
		1129599 MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48		BRD3_HUMAN (1073-1195): 1.37e-33: 143: 30.89
+	Hs
		674162 MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48		BRD2_HUMAN (1065-1195): 9.69e-34: 143: 30.53
+	Hs
		590279 MUC1_HUMAN (39-730): 2.41e-41: 165: 11.50		EP300_HUMAN (1789-2434): 7.34e-09: 63.6: 13.61
+	Hs
		698391 MAP4_HUMAN (22-721): 3.01e-10: 66.2: 9.24		TRI33_HUMAN (614-1207): 1.09e-36: 154: 13.64
+	Hs
		180852 SRCAP_HUMAN (168-756): 9.46e-12: 71.2: 11.72		TIF1A_HUMAN (667-1202): 2.18e-34: 147: 17.97
+	Dm
		119660 M9PB30_DROME (3-585): 4.93e-18: 91.6: 9.03		M9PB30_DROME (1836-2241): 2.87e-17: 91.8: 13.38
+	Hs
		1067330 MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48		EP300_HUMAN (1789-2434): 7.34e-09: 63.6: 13.61
+	Hs
		1401422 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		CHD7_HUMAN (105-479): 4.97e-11: 71: 9.19
+	Hs
		1067448 SRCAP_HUMAN (168-756): 9.46e-12: 71.2: 11.72		EP300_HUMAN (1789-2434): 7.34e-09: 63.6: 13.61
+	Hs
		161491 KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76		KMT2C_HUMAN (1839-2361): 2.29e-10: 68.7: 10.22
+	Hs
		698270 MAP4_HUMAN (22-721): 3.01e-10: 66.2: 9.24		EP300_HUMAN (1789-2434): 7.34e-09: 63.6: 13.61
+	Hs
		161457 KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76		EP300_HUMAN (1789-2434): 7.34e-09: 63.6: 13.61