HitPredict

Interactor 1: IRF1 (P10914)
Interferon regulatory factor 1 (IRF-1)
Gene: IRF1

Interactor 2: IL12A (P29459)
Interleukin-12 subunit alpha (IL-12A) (Cytotoxic lymphocyte maturation factor 35 kDa subunit) (CLMF p35) (IL-12 subunit p35) (NK cell stimulatory factor chain 1) (NKSF1)
Gene: IL12A

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.50	0.617

Property	Details
Experiments	19164128, 15489234, 18316378, 14568984
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 219
+	Mm
		583135 IRF1_MOUSE (1-325): 2.48e-161: 455: 84.50		IL12A_MOUSE (1-219): 8.54e-115: 328: 58.90
+	Hs
		712724 IRF8_HUMAN (7-270): 1.22e-99: 301: 28.79		IL12A_HUMAN (1-219): 1.84e-123: 350: 100.00
+	Hs
		712731 IRF3_HUMAN (1-263): 7.46e-62: 204: 21.29		IL12A_HUMAN (1-219): 1.84e-123: 350: 100.00
+	Hs
		712723 IRF9_HUMAN (7-267): 2.07e-56: 189: 26.02		IL12A_HUMAN (1-219): 1.84e-123: 350: 100.00
+	Hs
		712732 IRF4_HUMAN (7-207): 5.81e-56: 189: 27.36		IL12A_HUMAN (1-219): 1.84e-123: 350: 100.00
+	Hs
		712729 IRF5_HUMAN (2-297): 2.68e-54: 186: 24.05		IL12A_HUMAN (1-219): 1.84e-123: 350: 100.00
+	Hs
		712734 IRF7_HUMAN (4-252): 9.39e-41: 150: 21.09		IL12A_HUMAN (1-219): 1.84e-123: 350: 100.00