Interactor 1: KSS1 (P14681)
Mitogen-activated protein kinase KSS1 (MAP kinase KSS1) (EC 2.7.11.24) (Kinase suppressor of SST2)
Gene: KSS1

Interactor 2: STE11 (P23561)
Serine/threonine-protein kinase STE11 (EC 2.7.11.25)
Gene: STE11

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.920

The method score is based on:

Property Details
Experiments 7851759, 11805837, 11525741, 21118957, 8062390
Identification Methods two hybrid, anti tag coimmunoprecipitation, affinity chromatography technology, pull down, protein complementation assay
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000750 - pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0001402 - signal transduction involved in filamentous growth
GO:0001403 - invasive growth in response to glucose limitation
GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 368
Sc

1 717
+ Sc
+ Sc
+ At
+ Hs
+ Hs
+ At
+ Hs
+ At
+ Mm
+ At
+ Rn
+ Hs
+ Sc
+ Hs
+ Hs
+ At
+ Hs
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024