HitPredict

Interactor 1: DA (P11420)
Protein daughterless
Gene: DA

Interactor 2: Q9VL05 (Q9VL05)
FI14601p (Hand)
Gene: Hand

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	23747982
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 710 Dm			1 174
+	Dm
		1286100 Q86PA6_DROME (1-697): 0: 912: 96.84		Q86PA6_DROME (18-174): 3.15e-28: 111: 21.43
+	Dm
		542892 DA_DROME (1-710): 0: 908: 100.00		DA_DROME (18-174): 5.13e-28: 111: 21.43
+	Dm
		542918 DA_DROME (1-710): 0: 908: 100.00		FER3_DROME (19-174): 3.15e-30: 110: 22.44
+	Dm
		542905 DA_DROME (1-710): 0: 908: 100.00		ATO_DROME (1-115): 9.82e-26: 101: 28.45
+	Dm
		528890 DA_DROME (1-710): 0: 908: 100.00		TWIST_DROME (51-118): 4.64e-22: 93.7: 45.59
+	Dm
		542931 DA_DROME (1-710): 0: 908: 100.00		AMOS_DROME (53-118): 4.16e-23: 92.5: 42.42
+	Dm
		197543 DA_DROME (1-710): 0: 908: 100.00		O18374_DROME (49-116): 1.13e-20: 87.1: 39.71
+	Dm
		542910 DA_DROME (1-710): 0: 908: 100.00		Q0IGU7_DROME (49-116): 1.15e-20: 87.1: 39.71
+	Mm
		1222209 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		HAND2_MOUSE (11-169): 6.94e-28: 105: 45.12
+	Mm
		644331 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		TAL1_MOUSE (53-130): 9.94e-26: 102: 42.31
+	Mm
		688465 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		TWST1_MOUSE (50-123): 1.61e-26: 101: 52.00
+	Mm
		1222612 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		HAND1_MOUSE (37-169): 1.01e-25: 99.6: 45.07
+	Hs
		960659 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		HAND2_HUMAN (11-169): 6.94e-28: 105: 45.12
+	Hs
		1037885 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		HEN1_HUMAN (58-115): 6.49e-27: 100: 50.00
+	Hs
		605218 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		TAL1_HUMAN (53-130): 4.43e-25: 100: 42.31
+	Hs
		1088248 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		TCF15_HUMAN (21-159): 1.74e-25: 98.8: 29.80
+	Hs
		354061 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		HAND1_HUMAN (40-169): 6.58e-25: 97.7: 45.65
+	Hs
		223961 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		TCF21_HUMAN (13-126): 3.07e-25: 97.3: 31.58
+	Hs
		1037919 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		HEN2_HUMAN (62-115): 1.77e-25: 96.7: 50.00
+	Hs
		253544 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		MUSC_HUMAN (57-122): 1.26e-24: 96.7: 45.46