HitPredict

Interactor 1: DA (P11420)
Protein daughterless
Gene: DA

Interactor 2: Q0IGU7 (Q0IGU7)
HLH54F (RT01030p)
Gene: HLH54F

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	9486535
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 710 Dm			1 242
+	Dm
		197543 DA_DROME (1-710): 0: 908: 100.00		O18374_DROME (1-242): 2.54e-72: 222: 99.59
+	Dm
		542897 DA_DROME (1-710): 0: 908: 100.00		MYOD_DROME (7-211): 7.35e-38: 136: 21.26
+	Dm
		542918 DA_DROME (1-710): 0: 908: 100.00		FER3_DROME (5-139): 1.99e-27: 105: 25.93
+	Dm
		542905 DA_DROME (1-710): 0: 908: 100.00		ATO_DROME (14-88): 7.63e-26: 104: 34.67
+	Dm
		542929 DA_DROME (1-710): 0: 908: 100.00		Q9W4X2_DROME (31-141): 1.29e-25: 104: 28.10
+	Dm
		542921 DA_DROME (1-710): 0: 908: 100.00		Q9VL05_DROME (23-90): 1.25e-25: 100: 39.71
+	Dm
		542931 DA_DROME (1-710): 0: 908: 100.00		AMOS_DROME (32-90): 4.2e-11: 62.1: 42.37
+	Mm
		644331 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		TAL1_MOUSE (3-162): 1.12e-28: 112: 20.36
+	Mm
		1222209 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		HAND2_MOUSE (30-95): 8.73e-26: 102: 40.91
+	Mm
		1222612 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		HAND1_MOUSE (26-96): 1.31e-25: 101: 36.62
+	Hs
		581719 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		MYOD1_HUMAN (4-209): 4.3e-33: 123: 17.13
+	Mm
		688465 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		TWST1_MOUSE (23-123): 2.39e-25: 100: 28.85
+	Hs
		223961 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		TCF21_HUMAN (3-129): 1.02e-30: 113: 35.56
+	Hs
		605218 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		TAL1_HUMAN (3-162): 3.78e-28: 110: 20.12
+	Hs
		1088248 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		TCF15_HUMAN (32-122): 2.74e-26: 103: 32.97
+	Hs
		253544 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		MUSC_HUMAN (2-129): 2.2e-26: 103: 35.88
+	Hs
		960659 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		HAND2_HUMAN (30-95): 8.73e-26: 102: 40.91
+	Hs
		1037885 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		HEN1_HUMAN (31-88): 7.29e-25: 97.1: 41.38
+	Hs
		354061 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		HAND1_HUMAN (32-95): 8.86e-17: 77.9: 39.06
+	Hs
		1037919 HTF4_HUMAN (219-662): 5.89e-134: 412: 35.33		HEN2_HUMAN (34-88): 5.02e-11: 60.6: 41.82