HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: ACAC (Q00955)
Acetyl-CoA carboxylase (ACC) (EC 6.4.1.2) (Fatty acid synthetase 3) (mRNA transport-defective protein 7) [Includes: Biotin carboxylase (EC 6.3.4.14)]
Gene: ACC1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	19536198, 15766533
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 2233
+	Sc
		366744 HSP82_YEAST (1-705): 0: 968: 95.63		ACAC_YEAST (1-2233): 0: 2661: 100.00
+	Sc
		366031 HSP82_YEAST (1-705): 0: 968: 95.63		HFA1_YEAST (11-2225): 0: 2431: 55.14
+	Sc
		543404 HSC82_YEAST (1-705): 0: 977: 100.00		DUR1_YEAST (59-692): 2.26e-156: 533: 26.13
+	Sc
		424321 HSC82_YEAST (1-705): 0: 977: 100.00		PYR1_YEAST (28-484): 1.54e-46: 187: 14.96
+	Sc
		365577 HSP82_YEAST (1-705): 0: 968: 95.63		PYR1_YEAST (28-484): 1.54e-46: 187: 14.96
+	Sc
		372794 HSC82_YEAST (1-705): 0: 977: 100.00		CARB_YEAST (15-518): 8.04e-41: 168: 14.34
+	Sc
		365507 HSP82_YEAST (1-705): 0: 968: 95.63		CARB_YEAST (15-518): 8.04e-41: 168: 14.34
+	Sc
		543369 HSC82_YEAST (1-705): 0: 977: 100.00		PYC2_YEAST (665-776): 4.34e-23: 110: 23.48
+	Sc
		365956 HSP82_YEAST (1-705): 0: 968: 95.63		PYC2_YEAST (665-776): 4.34e-23: 110: 23.48