HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: SGT2 (Q12118)
Small glutamine-rich tetratricopeptide repeat-containing protein 2 (SGT/UBP) (Viral protein U-binding protein)
Gene: SGT2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.706

Property	Details
Experiments	31399574, 37295430, 20850366, 21832041, 17441508
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 705 Sc			1 346
+	Hs
		213454 HS90B_HUMAN (5-705): 0: 1022: 61.15		SGTA_HUMAN (3-321): 5.98e-50: 170: 28.53
+	Hs
		213451 HS90A_HUMAN (4-705): 0: 1013: 60.67		SGTA_HUMAN (3-321): 5.98e-50: 170: 28.53
+	Mm
		513680 HS90B_MOUSE (5-705): 0: 1025: 61.57		PPP5_MOUSE (99-304): 8.62e-43: 156: 26.70
+	Hs
		438021 HS90B_HUMAN (5-705): 0: 1022: 61.15		PPP5_HUMAN (99-304): 1.22e-42: 156: 26.21
+	Hs
		111935 K9JA46_HUMAN (4-705): 0: 1013: 60.67		PPP5_HUMAN (99-304): 1.22e-42: 156: 26.21
+	Hs
		431681 HS90A_HUMAN (4-705): 0: 1013: 60.67		PPP5_HUMAN (99-304): 1.22e-42: 156: 26.21
+	Mm
		513709 HS90B_MOUSE (5-705): 0: 1025: 61.57		CHIP_MOUSE (77-232): 1e-35: 133: 21.38
+	Hs
		438621 HS90B_HUMAN (5-705): 0: 1022: 61.15		CHIP_HUMAN (79-232): 1.12e-35: 133: 22.93
+	Hs
		438533 HS90B_HUMAN (5-705): 0: 1022: 61.15		RPAP3_HUMAN (98-302): 2.06e-29: 120: 21.74
+	Hs
		432268 HS90A_HUMAN (4-705): 0: 1013: 60.67		RPAP3_HUMAN (98-302): 2.06e-29: 120: 21.74
+	Hs
		437930 HS90B_HUMAN (5-705): 0: 1022: 61.15		STIP1_HUMAN (91-278): 5.7e-22: 98.5: 21.54
+	Hs
		438201 HS90B_HUMAN (5-705): 0: 1022: 61.15		TOM34_HUMAN (94-278): 5.34e-22: 96.5: 20.21
+	Hs
		174561 HS90B_HUMAN (5-705): 0: 1022: 61.15		OGT1_HUMAN (96-322): 3.35e-19: 90.8: 13.73
+	Hs
		431774 HS90A_HUMAN (4-705): 0: 1013: 60.67		SPAG1_HUMAN (71-297): 4.22e-22: 99.5: 17.01
+	Hs
		111934 K9JA46_HUMAN (4-705): 0: 1013: 60.67		STIP1_HUMAN (91-278): 5.7e-22: 98.5: 21.54
+	Hs
		431574 HS90A_HUMAN (4-705): 0: 1013: 60.67		STIP1_HUMAN (91-278): 5.7e-22: 98.5: 21.54
+	Hs
		431886 HS90A_HUMAN (4-705): 0: 1013: 60.67		TOM34_HUMAN (94-278): 5.34e-22: 96.5: 20.21
+	Hs
		174556 HS90A_HUMAN (4-705): 0: 1013: 60.67		OGT1_HUMAN (96-322): 3.35e-19: 90.8: 13.73
+	Hs
		438464 HS90B_HUMAN (5-705): 0: 1022: 61.15		DNJC7_HUMAN (99-221): 7.06e-10: 62: 33.07
+	Hs
		432195 HS90A_HUMAN (4-705): 0: 1013: 60.67		DNJC7_HUMAN (99-221): 7.06e-10: 62: 33.07