HitPredict

Interactor 1: INSR (P15127)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: TBA4A (Q5XIF6)
Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 4) (Tubulin alpha-4 chain)
Gene: Tuba4a

Species: Rattus norvegicus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	30300385
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005525 - GTP binding GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1383 Rn			1 448
+	Hs
		411416 INSR_HUMAN (27-1383): 0: 1527: 95.43		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		411272 INSR_HUMAN (27-1383): 0: 1527: 95.43		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		435607 IGF1R_HUMAN (13-1381): 0: 1302: 55.77		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		665575 EPHB2_HUMAN (662-1317): 0: 577: 23.01		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		933452 EPHA7_HUMAN (664-1321): 0: 568: 22.55		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		1072528 EPHA7_HUMAN (664-1321): 0: 568: 22.55		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		428109 EPHA4_HUMAN (662-1328): 0: 570: 24.19		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		428222 EPHA7_HUMAN (664-1321): 0: 568: 22.55		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		872631 EPHA4_HUMAN (662-1328): 0: 570: 24.19		TBB4B_HUMAN (1-437): 0: 695: 40.28
+	Hs
		872702 EPHA4_HUMAN (662-1328): 0: 570: 24.19		TBB2B_HUMAN (1-440): 0: 694: 39.77
+	Hs
		872523 EPHB4_HUMAN (662-1321): 3.03e-170: 536: 24.96		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		665203 EPHA2_HUMAN (662-1321): 2.76e-167: 528: 22.70		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		934024 ALK_HUMAN (997-1340): 6.12e-71: 264: 41.57		TBB4B_HUMAN (1-437): 0: 695: 40.28
+	Hs
		385049 NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		384107 NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		384633 NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95		TBB4B_HUMAN (1-437): 0: 695: 40.28
+	Hs
		385452 NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95		TBB2B_HUMAN (1-440): 0: 694: 39.77
+	Hs
		385617 NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95		TBA8_HUMAN (1-440): 0: 691: 90.23
+	Hs
		601882 ERBB3_HUMAN (5-368): 5.74e-31: 135: 19.70		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		428019 ERBB3_HUMAN (5-368): 5.74e-31: 135: 19.70		TBB5_HUMAN (1-439): 0: 697: 40.55