Interactor 1: RYR1 (P11716)
Ryanodine receptor 1 (RYR-1) (RyR1) (Skeletal muscle calcium release channel) (Skeletal muscle ryanodine receptor) (Skeletal muscle-type ryanodine receptor) (Type 1 ryanodine receptor)
Gene: RYR1
Interactor 2: FKB1A (P62943)
Peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Calstabin-1) (FK506-binding protein 1A) (FKBP-1A) (Immunophilin FKBP12) (Rotamase)
Gene: FKBP1A
Species: Oryctolagus cuniculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.666 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25517095 |
| Identification Methods | 3D electron microscopy, molecular sieving |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FKBP_C~RYDR_ITPR, FKBP_C~RYDR_Jsol, FKBP_C~SPRY |
| Common GO terms | GO:0014802 - terminal cisterna GO:0016529 - sarcoplasmic reticulum GO:1990425 - ryanodine receptor complex |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025