HitPredict

Interactor 1: DESP (P15924)
Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)
Gene: DSP

Interactor 2: WSB1 (Q9Y6I7)
WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box-containing WD protein SWiP-1)
Gene: WSB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2871 Hs			1 421
+	Hs
		551632 DESP_HUMAN (1-2871): 0: 818: 100.00		LIS1_HUMAN (2-286): 2.98e-83: 262: 20.72
+	Hs
		551655 DESP_HUMAN (1-2871): 0: 818: 100.00		WDR5_HUMAN (295-420): 1.65e-30: 121: 15.27
+	Hs
		551854 DESP_HUMAN (1-2871): 0: 818: 100.00		NLE1_HUMAN (298-418): 5.4e-28: 117: 18.94
+	Hs
		551858 DESP_HUMAN (1-2871): 0: 818: 100.00		WSB2_HUMAN (2-198): 1.18e-28: 117: 15.50
+	Hs
		551766 DESP_HUMAN (1-2871): 0: 818: 100.00		WDR5B_HUMAN (285-420): 5.67e-27: 111: 13.48
+	Hs
		1068625 PLEC_HUMAN (20-1265): 9.18e-42: 172: 9.33		FBXW7_HUMAN (2-334): 4.09e-75: 249: 19.05
+	Hs
		792973 CENPE_HUMAN (1293-2534): 2.34e-36: 154: 10.36		LIS1_HUMAN (2-286): 2.98e-83: 262: 20.72
+	Mm
		925837 Q155P7_MOUSE (23-636): 6.99e-16: 87.3: 7.13		LIS1_MOUSE (2-286): 2e-83: 263: 20.72
+	Hs
		1281478 MACF1_HUMAN (1987-2820): 9.45e-10: 67.2: 12.38		FBXW7_HUMAN (2-334): 4.09e-75: 249: 19.05
+	Hs
		903240 PLEC_HUMAN (20-1265): 9.18e-42: 172: 9.33		WDR5_HUMAN (295-420): 1.65e-30: 121: 15.27
+	Hs
		903212 SPTN1_HUMAN (235-2163): 6.27e-28: 126: 9.67		WDR5_HUMAN (295-420): 1.65e-30: 121: 15.27
+	Hs
		234241 PEPL_HUMAN (1428-2565): 6.62e-28: 126: 14.08		WDR5B_HUMAN (285-420): 5.67e-27: 111: 13.48
+	Hs
		903233 GOGB1_HUMAN (1530-2529): 4.77e-20: 101: 9.08		WDR5_HUMAN (295-420): 1.65e-30: 121: 15.27
+	Hs
		885220 EPIPL_HUMAN (2574-2832): 1.51e-11: 73.1: 15.71		WDR5_HUMAN (295-420): 1.65e-30: 121: 15.27
+	Hs
		903137 SPTB2_HUMAN (1169-2330): 8.03e-10: 67.2: 8.93		WDR5_HUMAN (295-420): 1.65e-30: 121: 15.27
+	Hs
		903607 MACF1_HUMAN (1987-2820): 9.45e-10: 67.2: 12.38		WDR5_HUMAN (295-420): 1.65e-30: 121: 15.27
+	Hs
		1313659 MACF1_HUMAN (1987-2820): 9.45e-10: 67.2: 12.38		KTNB1_HUMAN (39-210): 4.15e-21: 97.8: 20.35