HitPredict

Interactor 1: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Interactor 2: PXDN (Q92626)
Peroxidasin homolog (EC 1.11.2.-) (Melanoma-associated antigen MG50) (Peroxidasin 1) (hsPxd01) (Vascular peroxidase 1) (p53-responsive gene 2 protein) [Cleaved into: PXDN active fragment]
Gene: PXDN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	I-set~I-set, I-set~LRR_8, LRR_8~PK_Tyr_Ser-Thr
Common GO terms	GO:0030198 - extracellular matrix organization
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1089 Hs			1 1479
+	Hs
		557225 PGFRA_HUMAN (1-1089): 0: 817: 100.00		LRIG1_HUMAN (1-212): 1.61e-24: 113: 21.51
+	Hs
		299549 PGFRB_HUMAN (29-1089): 0: 650: 43.33		LRIG2_HUMAN (3-712): 9.31e-62: 233: 16.37
+	Dr
		65451 VGFR4_DANRE (110-787): 8.42e-39: 159: 11.55		A8DZ85_DANRE (342-941): 4.67e-74: 274: 17.48
+	Hs
		608212 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		ROBO1_HUMAN (310-1017): 1.82e-78: 289: 17.50
+	Hs
		299548 RET_HUMAN (573-690): 7.85e-22: 104: 43.22		LRIG2_HUMAN (3-712): 9.31e-62: 233: 16.37
+	Mm
		724165 RET_MOUSE (575-690): 9.48e-23: 107: 44.83		LRIG1_MOUSE (46-216): 1.13e-23: 111: 22.37
+	Hs
		434263 RET_HUMAN (573-690): 7.85e-22: 104: 43.22		LRIG1_HUMAN (1-212): 1.61e-24: 113: 21.51