Protein: PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2)

Gene: PP6R2, PPP6R2
Organism: Homo sapiens
Interactions: 113
UniProt ID: O75170

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0019888 - protein phosphatase regulator activity
GO:0019903 - protein phosphatase binding
GO:0036464 - cytoplasmic ribonucleoprotein granule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

135321

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

10

9

Small-scale

0.758

High

257169

PLK1
Serine/threonine-protein kinase PLK1

8

12

Small-scale

0.753

High

160281

AURKA
Aurora kinase A

6

4

High-throughput

0.733

High

166864

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

5

11

Small-scale

0.723

High

257200

ANR52
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

4

11

High-throughput

0.706

High

257173

PRKDC
DNA-dependent protein kinase catalytic subunit

3

7

Small-scale

0.681

High

257177

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

3

8

High-throughput

0.667

High

257199

ANR44
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B

4

11

High-throughput

0.633

High

66631

ZN785
Zinc finger protein 785

2

1

High-throughput

0.628

High

161486

S27A2
Long-chain fatty acid transport protein 2

2

1

High-throughput

0.628

High

212577

AP1G1
AP-1 complex subunit gamma-1

2

13

High-throughput

0.628

High

257171

AP1S2
AP-1 complex subunit sigma-2

2

4

High-throughput

0.628

High

257175

AP1B1
AP-1 complex subunit beta-1

2

12

High-throughput

0.628

High

257182

KCC4
Calcium/calmodulin-dependent protein kinase type IV

2

3

High-throughput

0.628

High

257189

ACD11
Acyl-CoA dehydrogenase family member 11

2

3

High-throughput

0.628

High

257196

TRM2A
tRNA

2

2

High-throughput

0.628

High

257197

ASPM
Abnormal spindle-like microcephaly-associated protein

2

6

High-throughput

0.628

High

257239

MYO5A
Unconventional myosin-Va

2

5

High-throughput

0.628

High

257193

MOB1B
MOB kinase activator 1B

2

9

High-throughput

0.621

High

257208

AP2M1
AP-2 complex subunit mu

2

1

High-throughput

0.611

High

257223

MOB1A
MOB kinase activator 1A

2

9

High-throughput

0.611

High

257187

ZN574
Zinc finger protein 574

2

0

High-throughput

0.602

High

257201

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

2

0

High-throughput

0.602

High

257213

DCR1C
Protein artemis

3

1

High-throughput

0.599

High

132682

SDCB1
Syntenin-1

2

5

Small-scale

0.595

High

121552

IKBE
NF-kappa-B inhibitor epsilon

2

17

Small-scale

0.584

High

257230

ZRAN1
Ubiquitin thioesterase ZRANB1

2

5

High-throughput

0.584

High

257160

GDC
Solute carrier family 25 member 16

2

3

High-throughput

0.574

High

257205

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

2

1

High-throughput

0.574

High

257225

MYO5C
Unconventional myosin-Vc

2

4

High-throughput

0.574

High

257234

MYO5B
Unconventional myosin-Vb

2

4

High-throughput

0.574

High

217113

EXTL3
Exostosin-like 3

1

1

High-throughput

0.536

High

225114

MYPT2
Protein phosphatase 1 regulatory subunit 12B

1

14

High-throughput

0.536

High

239291

CC14B
Dual specificity protein phosphatase CDC14B

1

7

High-throughput

0.536

High

257152

AP2A1
AP-2 complex subunit alpha-1

1

13

High-throughput

0.536

High

257164

SRP14
Signal recognition particle 14 kDa protein

1

1

High-throughput

0.536

High

257166

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

2

High-throughput

0.536

High

257167

KS6A3
Ribosomal protein S6 kinase alpha-3

1

3

High-throughput

0.536

High

257183

FX4L6
Forkhead box protein D4-like 6

1

5

High-throughput

0.536

High

257203

ZNRF2
E3 ubiquitin-protein ligase ZNRF2

1

2

High-throughput

0.536

High

257207

EFMT3
EEF1A lysine methyltransferase 3

1

4

High-throughput

0.536

High

257217

NPAS1
Neuronal PAS domain-containing protein 1

1

5

High-throughput

0.536

High

257235

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.536

High

257204

ARHG2
Rho guanine nucleotide exchange factor 2

1

6

Small-scale

0.515

High

257165

HD
Huntingtin

1

5

High-throughput

0.515

High

257158

PIP
Prolactin-inducible protein

1

0

High-throughput

0.513

High

257221

S26A6
Solute carrier family 26 member 6

1

0

High-throughput

0.513

High

257170

ATX1
Ataxin-1

1

1

High-throughput

0.508

High

257154

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

50062

HACL2
2-hydroxyacyl-CoA lyase 2

1

2

High-throughput

0.489

High

257149

MYO1D
Unconventional myosin-Id

1

5

High-throughput

0.489

High

257151

ACSL3
Fatty acid CoA ligase Acsl3

1

2

High-throughput

0.489

High

257157

WNT2
Protein Wnt-2

1

3

High-throughput

0.489

High

257168

RM12
Large ribosomal subunit protein bL12m

1

1

High-throughput

0.489

High

257206

EMID1
EMI domain-containing protein 1

1

1

High-throughput

0.489

High

162259

XPO1
Exportin-1

1

14

High-throughput

0.479

High

226037

PRKN
E3 ubiquitin-protein ligase parkin

1

14

High-throughput

0.479

High

257147

TULP3
Tubby-related protein 3

1

1

High-throughput

0.479

High

257148

RECQ4
ATP-dependent DNA helicase Q4

1

6

High-throughput

0.479

High

257150

EPM2A
Laforin

1

1

High-throughput

0.479

High

257155

K2C8
Keratin, type II cytoskeletal 8

1

3

High-throughput

0.479

High

257156

PROF1
Profilin-1

1

3

High-throughput

0.479

High

257161

MARK3
MAP/microtubule affinity-regulating kinase 3

1

4

High-throughput

0.479

High

257162

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

257172

AP2B1
AP-2 complex subunit beta

1

12

High-throughput

0.479

High

257174

ACK1
Activated CDC42 kinase 1

1

13

High-throughput

0.479

High

257176

CUL3
Cullin-3

1

7

High-throughput

0.479

High

257178

KS6A2
Ribosomal protein S6 kinase alpha-2

1

3

High-throughput

0.479

High

257179

EZH2
Histone-lysine N-methyltransferase EZH2

1

5

High-throughput

0.479

High

257180

ZYX
Zyxin

1

6

High-throughput

0.479

High

257181

CCDC6
Coiled-coil domain-containing protein 6

1

7

High-throughput

0.479

High

257184

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

7

High-throughput

0.479

High

257185

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.479

High

257191

MOB3C
MOB kinase activator 3C

1

9

High-throughput

0.479

High

257194

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.479

High

257198

PNKD
Probable hydrolase PNKD

1

1

High-throughput

0.479

High

257202

NUP43
Nucleoporin Nup43

1

6

High-throughput

0.479

High

257214

PFD5
Prefoldin subunit 5

1

1

High-throughput

0.479

High

257215

DNJC2
DnaJ homolog subfamily C member 2

1

7

High-throughput

0.479

High

257216

TTC1
Tetratricopeptide repeat protein 1

1

4

High-throughput

0.479

High

257222

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

257226

SHLB2
Endophilin-B2

1

16

High-throughput

0.479

High

257227

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

3

High-throughput

0.479

High

257231

TBK1
Serine/threonine-protein kinase TBK1

1

6

High-throughput

0.479

High

257232

PFD2
Prefoldin subunit 2

1

1

High-throughput

0.479

High

257236

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

7

High-throughput

0.479

High

257237

RUVB2
RuvB-like 2

1

2

High-throughput

0.479

High

257238

NUDC
Nuclear migration protein nudC

1

1

High-throughput

0.479

High

257240

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

2

High-throughput

0.479

High

257190

UBP49
Ubiquitin carboxyl-terminal hydrolase 49

1

6

High-throughput

0.470

High

118653

AIP
AH receptor-interacting protein

1

0

High-throughput

0.458

High

257220

DPCD
Protein DPCD

1

0

High-throughput

0.458

High

257224

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

257228

HYPK
Huntingtin-interacting protein K

1

0

Small-scale

0.458

High

257209

SPTCS
Spatacsin

1

0

Small-scale

0.438

High

135518

WN10B
Protein Wnt-10b

1

3

High-throughput

0.437

High

171562

PFD6
Prefoldin subunit 6

1

1

High-throughput

0.437

High

204821

TGON2
Trans-Golgi network integral membrane protein 2

1

10

High-throughput

0.437

High

257153

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.437

High

257159

PRG2
Bone marrow proteoglycan

1

2

High-throughput

0.437

High

257163

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

257186

FBX42
F-box only protein 42

1

1

High-throughput

0.437

High

257188

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

257192

MARK2
Serine/threonine-protein kinase MARK2

1

5

High-throughput

0.437

High

257195

HOOK3
Protein Hook homolog 3

1

7

High-throughput

0.437

High

257210

HS12B
Heat shock 70 kDa protein 12B

1

1

High-throughput

0.437

High

257212

RB40C
Ras-related protein Rab-40C

1

4

Small-scale

0.437

High

257229

MARK1
Serine/threonine-protein kinase MARK1

1

4

High-throughput

0.437

High

257233

DS13B
Dual specificity protein phosphatase 13B

1

4

High-throughput

0.437

High

127417

RPOM
DNA-directed RNA polymerase, mitochondrial

2

0

High-throughput

0.328

High

257218

GORS1
Golgi reassembly-stacking protein 1

2

0

High-throughput

0.328

High

257219

TMM43
Transmembrane protein 43

1

0

High-throughput

0.279

Low

257211

DAA10
Dynein axonemal assembly factor 10

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024