Protein: 3BP2
SH3 domain-binding protein 2 (3BP-2)

Gene: 3BP2, SH3BP2
Organism: Homo sapiens
Interactions: 46
UniProt ID: P78314

Gene Ontology (top 5):
GO:0001784 - phosphotyrosine residue binding
GO:0007165 - signal transduction
GO:0017124 - SH3 domain binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

584515

VAV
Proto-oncogene vav

4

10

Small-scale

0.918

High

849140

KSYK
Tyrosine-protein kinase SYK

3

20

Small-scale

0.821

High

913638

VAV2
Guanine nucleotide exchange factor VAV2

2

11

Small-scale

0.786

High

571669

HCLS1
Hematopoietic lineage cell-specific protein

2

20

High-throughput

0.783

High

49963

RHG10
Rho GTPase-activating protein 10

2

2

High-throughput

0.767

High

619026

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

3

1

Small-scale

0.763

High

849063

ZAP70
Tyrosine-protein kinase ZAP-70

1

20

Small-scale

0.724

High

123910

MYO1F
Unconventional myosin-If

2

7

High-throughput

0.700

High

472037

MET
Hepatocyte growth factor receptor

1

7

High-throughput

0.692

High

532069

KIT
Mast/stem cell growth factor receptor Kit

1

3

High-throughput

0.692

High

362239

ABL1
Tyrosine-protein kinase ABL1

1

15

High-throughput

0.647

High

410762

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

12

High-throughput

0.647

High

641564

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

14

High-throughput

0.647

High

987528

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.647

High

1004308

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

16

High-throughput

0.647

High

1004311

SH3K1
SH3 domain-containing kinase-binding protein 1

2

15

Small-scale

0.644

High

1004317

DBNL
Drebrin-like protein

3

19

Small-scale

0.623

High

827738

STAT3
Signal transducer and activator of transcription 3

1

1

High-throughput

0.621

High

557216

SRC
Proto-oncogene tyrosine-protein kinase Src

1

15

Small-scale

0.618

High

1004306

SRC8
Src substrate cortactin

2

20

High-throughput

0.606

High

651274

CBL
E3 ubiquitin-protein ligase CBL

2

3

Small-scale

0.595

High

711092

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

0

Small-scale

0.593

High

1004313

TNKS2
Poly [ADP-ribose] polymerase tankyrase-2

2

5

Small-scale

0.593

High

690896

1433T
14-3-3 protein theta

1

20

Small-scale

0.581

High

440023

LCK
Tyrosine-protein kinase Lck

1

15

Small-scale

0.575

High

599282

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

1

Small-scale

0.575

High

440483

FYN
Tyrosine-protein kinase Fyn

1

15

Small-scale

0.555

High

541433

FGFR1
Fibroblast growth factor receptor 1

1

4

Small-scale

0.555

High

1004309

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

16

High-throughput

0.555

High

1004318

VAV3
Guanine nucleotide exchange factor VAV3

1

12

Small-scale

0.553

High

220368

LAT
Linker for activation of T-cells family member 1

2

1

Small-scale

0.543

High

1004315

PDLI7
PDZ and LIM domain protein 7

1

3

High-throughput

0.494

High

947339

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

1

Small-scale

0.457

High

1004312

CD244
Natural killer cell receptor 2B4

1

3

Small-scale

0.457

High

172691

XPO1
Exportin-1

1

1

High-throughput

0.437

High

272068

OBSL1
Obscurin-like protein 1

1

10

High-throughput

0.437

High

332397

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

1

5

Small-scale

0.437

High

639711

TAF1
Transcription initiation factor TFIID subunit 1

1

2

High-throughput

0.437

High

659205

SP100
Nuclear autoantigen Sp-100

1

6

High-throughput

0.437

High

674133

BRD2
Bromodomain-containing protein 2

1

4

High-throughput

0.437

High

1004307

CUL7
Cullin-7

1

2

High-throughput

0.437

High

1004314

SP110
Sp110 nuclear body protein

1

5

High-throughput

0.437

High

1004305

IKZF1
DNA-binding protein Ikaros

1

0

Small-scale

0.249

Low

1004316

RN146
E3 ubiquitin-protein ligase RNF146

1

0

Small-scale

0.249

Low

390883

TRFE
Serotransferrin

1

0

High-throughput

0.238

Low

1004310

HAVR2
Hepatitis A virus cellular receptor 2

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025