Interactor 1: LYL1 (P12980)
Protein lyl-1 (Class A basic helix-loop-helix protein 18) (bHLHa18) (Lymphoblastic leukemia-derived sequence 1)
Gene: LYL1
Interactor 2: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.54 | 0.60 | 0.573 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10023675 |
| Identification Methods | pull down, affinity chromatography technology, two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II and 1 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025