Interactor 1: APKC (A1Z9X0)
Atypical protein kinase C (EC 2.7.11.13)
Gene: APKC

Interactor 2: O97111 (O97111)
LD29223p (PAR-6) (Par-6, isoform B)
Gene: par-6

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 12629552, 22036573, 22174071, 15177032, 18854163, 19375318, 19789180, 31405903, 27089924, 15907474, 14605208, 38944040
Identification Methods affinity chromatography technology, two hybrid, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PB1~PB1, PB1~Pkinase
Common GO terms GO:0001738 - morphogenesis of a polarized epithelium
GO:0005938 - cell cortex
GO:0007416 - synapse assembly
GO:0007430 - terminal branching, open tracheal system
GO:0010592 - positive regulation of lamellipodium assembly
and 13 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 606
Dm

1 351
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Ce
+ Hs
+ Ce
+ Rn
+ Hs
+ Rn
+ Mm
+ Mm
+ Mm

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Last updated: 11Aug2025