HitPredict

Interactor 1: UBF1 (P17480)
Nucleolar transcription factor 1 (Autoantigen NOR-90) (Upstream-binding factor 1) (UBF-1)
Gene: UBTF

Interactor 2: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34732716
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HMG_box~HMG_box, HMG_box~HMG_box_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 764 Hs			1 317
+	Hs
		567772 UBF1_HUMAN (1-677): 0: 606: 100.00		TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75
+	Hs
		818329 SMCE1_HUMAN (116-379): 4.65e-34: 137: 14.60		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818487 HM20A_HUMAN (91-288): 4.63e-27: 115: 20.98		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		817923 TFAM_HUMAN (112-287): 2.6e-24: 104: 20.10		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		727808 HM20A_HUMAN (91-288): 4.63e-27: 115: 20.98		SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27
+	Hs
		1281244 SMCE1_HUMAN (116-379): 4.65e-34: 137: 14.60		SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19
+	Hs
		727727 TFAM_HUMAN (112-287): 2.6e-24: 104: 20.10		SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27
+	Dm
		114544 M9PCZ7_DROME (104-184): 3.27e-24: 110: 23.46		M9PFG6_DROME (21-121): 2.56e-40: 147: 78.22
+	Hs
		1342331 HM20A_HUMAN (91-288): 4.63e-27: 115: 20.98		HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32
+	Hs
		881829 HM20A_HUMAN (91-288): 4.63e-27: 115: 20.98		SOX10_HUMAN (28-219): 8.75e-34: 130: 35.42
+	Hs
		1342340 HM20A_HUMAN (91-288): 4.63e-27: 115: 20.98		HM20B_HUMAN (11-249): 2.15e-33: 126: 17.77
+	Hs
		959048 TFAM_HUMAN (112-287): 2.6e-24: 104: 20.10		SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19
+	Hs
		727930 HM20A_HUMAN (91-288): 4.63e-27: 115: 20.98		SOX6_HUMAN (29-244): 2.42e-29: 120: 23.61
+	Hs
		225791 HM20A_HUMAN (91-288): 4.63e-27: 115: 20.98		SOX15_HUMAN (13-118): 1.78e-31: 119: 66.04
+	Hs
		881795 TFAM_HUMAN (112-287): 2.6e-24: 104: 20.10		SOX10_HUMAN (28-219): 8.75e-34: 130: 35.42
+	Hs
		959010 TFAM_HUMAN (112-287): 2.6e-24: 104: 20.10		CIC_HUMAN (3-272): 8.9e-33: 130: 22.26
+	Hs
		958886 TFAM_HUMAN (112-287): 2.6e-24: 104: 20.10		SOX4_HUMAN (9-289): 2.6e-33: 129: 26.69
+	Hs
		727847 TFAM_HUMAN (112-287): 2.6e-24: 104: 20.10		SOX6_HUMAN (29-244): 2.42e-29: 120: 23.61
+	Hs
		225726 TFAM_HUMAN (112-287): 2.6e-24: 104: 20.10		SOX15_HUMAN (13-118): 1.78e-31: 119: 66.04
+	Dm
		1098030 HMG2_DROME (187-364): 3.11e-19: 92.7: 16.30		DICH_DROME (41-117): 1.19e-33: 129: 88.31