Protein: BRD8
Bromodomain-containing protein 8 (Skeletal muscle abundant protein) (Skeletal muscle abundant protein 2) (Thyroid hormone receptor coactivating protein of 120 kDa) (TrCP120) (p120)

Gene: BRD8
Organism: Homo sapiens
Interactions: 147
UniProt ID: Q9H0E9

Gene Ontology (top 5):
GO:0000786 - nucleosome
GO:0000812 - Swr1 complex
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1429950

MO4L1
Mortality factor 4-like protein 1

11

2

Small-scale

0.755

High

260435

BRD4
Bromodomain-containing protein 4

2

20

High-throughput

0.754

High

1371281

KAT5
Histone acetyltransferase KAT5

7

13

Small-scale

0.747

High

1136854

MO4L2
Mortality factor 4-like protein 2

8

2

Small-scale

0.746

High

1429956

RUVB2
RuvB-like 2

7

9

High-throughput

0.744

High

1396740

EP400
E1A-binding protein p400

6

20

Small-scale

0.732

High

1429942

DMAP1
DNA methyltransferase 1-associated protein 1

6

1

Small-scale

0.727

High

1429944

MRGBP
MRG/MORF4L-binding protein

11

0

Small-scale

0.724

High

340403

YETS4
YEATS domain-containing protein 4

5

10

High-throughput

0.718

High

1429957

RUVB1
RuvB-like 1

5

9

High-throughput

0.714

High

1429949

MS18A
Protein Mis18-alpha

1

0

High-throughput

0.702

High

1244938

FOXR1
Forkhead box protein R1

4

15

High-throughput

0.699

High

1429959

TRRAP
Transformation/transcription domain-associated protein

4

20

High-throughput

0.699

High

1053309

MBTD1
MBT domain-containing protein 1

4

2

Small-scale

0.694

High

833775

KDM5C
Lysine-specific demethylase 5C

1

12

High-throughput

0.691

High

502120

H2AZ
Histone H2A.Z

4

20

Small-scale

0.691

High

1381858

H2B1A
Histone H2B type 1-A

4

20

High-throughput

0.691

High

51493

FSD2
Fibronectin type III and SPRY domain-containing protein 2

3

13

High-throughput

0.675

High

1245359

FOXR2
Forkhead box protein R2

3

15

High-throughput

0.667

High

1429936

EAF6
Chromatin modification-related protein MEAF6

4

0

High-throughput

0.661

High

1429933

EPC1
Enhancer of polycomb homolog 1

3

3

Small-scale

0.656

High

1429947

ING3
Inhibitor of growth protein 3

3

12

Small-scale

0.656

High

1155326

VPS72
Vacuolar protein sorting-associated protein 72 homolog

3

2

Small-scale

0.650

High

373110

MYC
Myc proto-oncogene protein

3

20

High-throughput

0.640

High

959653

MAX
Protein max

3

20

Small-scale

0.640

High

981081

H2B1C
Histone H2B type 1-C/E/F/G/I

3

20

High-throughput

0.640

High

553763

MYCL
Protein L-Myc

2

20

High-throughput

0.628

High

1291980

JAZF1
Juxtaposed with another zinc finger protein 1

3

0

Small-scale

0.628

High

639819

TAF1
Transcription initiation factor TFIID subunit 1

1

19

High-throughput

0.618

High

711841

KDM5A
Lysine-specific demethylase 5A

1

11

High-throughput

0.618

High

1401047

PHF12
PHD finger protein 12

1

17

High-throughput

0.618

High

1429932

BRD8
Bromodomain-containing protein 8

1

18

High-throughput

0.618

High

1429953

BRPF3
Bromodomain and PHD finger-containing protein 3

1

20

High-throughput

0.618

High

1198114

EPC2
Enhancer of polycomb homolog 2

2

3

High-throughput

0.611

High

1429938

PLAC1
Placenta-specific protein 1

3

1

High-throughput

0.609

High

1109383

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

2

1

High-throughput

0.606

High

1390159

MCRS1
Microspherule protein 1

2

1

High-throughput

0.606

High

414588

P53
Cellular tumor antigen p53

2

20

High-throughput

0.584

High

396909

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

593211

CREB1
Cyclic AMP-responsive element-binding protein 1

1

9

High-throughput

0.536

High

682606

S100P
Protein S100-P

1

4

High-throughput

0.536

High

872730

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.536

High

953092

ACTB
Actin, cytoplasmic 1

1

19

High-throughput

0.536

High

1323979

H2B3B
Histone H2B type 3-B

1

20

High-throughput

0.536

High

1361577

ING5
Inhibitor of growth protein 5

1

11

High-throughput

0.536

High

1404381

CDC5L
Cell division cycle 5-like protein

1

14

High-throughput

0.536

High

1429951

IPO11
Importin-11

1

13

High-throughput

0.536

High

533365

THB
Thyroid hormone receptor beta

1

20

Small-scale

0.527

High

625844

RXRA
Retinoic acid receptor RXR-alpha

1

20

Small-scale

0.527

High

2029

A0A0A0MR80
E1A binding protein p400

1

20

High-throughput

0.515

High

720694

AGTR1
Type-1 angiotensin II receptor

1

1

High-throughput

0.494

High

706305

S10A2
Protein S100-A2

1

4

High-throughput

0.489

High

1311239

UN45B
Protein unc-45 homolog B

1

9

High-throughput

0.489

High

1429943

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

2

High-throughput

0.489

High

124484

HAX1
HCLS1-associated protein X-1

1

1

High-throughput

0.479

High

143471

E2F3
Transcription factor E2F3

1

16

Small-scale

0.479

High

163163

CHK1
Serine/threonine-protein kinase Chk1

1

2

High-throughput

0.479

High

186800

P73
Tumor protein p73

1

20

High-throughput

0.479

High

274378

SIN3B
Paired amphipathic helix protein Sin3b

1

6

High-throughput

0.479

High

296297

SCO1
Protein SCO1 homolog, mitochondrial

1

3

High-throughput

0.479

High

339850

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

355291

ACL6A
Actin-like protein 6A

1

20

High-throughput

0.479

High

520361

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

569333

MTDC
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase

1

5

High-throughput

0.479

High

607095

CEBPB
CCAAT/enhancer-binding protein beta

1

20

High-throughput

0.479

High

644045

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

2

High-throughput

0.479

High

675670

TYY1
Transcriptional repressor protein YY1

1

20

High-throughput

0.479

High

714414

PML
Protein PML

1

20

High-throughput

0.479

High

791706

SYUA
Alpha-synuclein

1

4

Small-scale

0.479

High

834049

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

837087

ELK3
ETS domain-containing protein Elk-3

1

20

High-throughput

0.479

High

862439

YAP1
Transcriptional coactivator YAP1

1

16

High-throughput

0.479

High

905672

IRAK1
Interleukin-1 receptor-associated kinase 1

1

2

High-throughput

0.479

High

912008

DGKE
Diacylglycerol kinase epsilon

1

3

High-throughput

0.479

High

957511

UBC12
NEDD8-conjugating enzyme Ubc12

1

10

High-throughput

0.479

High

980295

H4
Histone H4

1

20

High-throughput

0.479

High

1024176

TFAM
Transcription factor A, mitochondrial

1

20

High-throughput

0.479

High

1033215

EWS
RNA-binding protein EWS

1

17

High-throughput

0.479

High

1048093

TLE3
Transducin-like enhancer protein 3

1

16

High-throughput

0.479

High

1058642

CKAP4
Cytoskeleton-associated protein 4

1

20

High-throughput

0.479

High

1102647

MTA1
Metastasis-associated protein MTA1

1

20

High-throughput

0.479

High

1140828

KIF14
Kinesin-like protein KIF14

1

10

High-throughput

0.479

High

1152738

ELF2
ETS-related transcription factor Elf-2

1

20

High-throughput

0.479

High

1247629

SAMD1
Sterile alpha motif domain-containing protein 1

1

15

High-throughput

0.479

High

1278972

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

20

High-throughput

0.479

High

1281403

COXM1
COX assembly mitochondrial protein homolog

1

1

High-throughput

0.479

High

1312250

MIRO2
Mitochondrial Rho GTPase 2

1

16

High-throughput

0.479

High

1313421

SMC5
Structural maintenance of chromosomes protein 5

1

20

High-throughput

0.479

High

1338953

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

1341314

COQ8A
Atypical kinase COQ8A, mitochondrial

1

3

High-throughput

0.479

High

1357149

GATD1
GATA zinc finger domain-containing protein 1

1

1

High-throughput

0.479

High

1370903

GCDH
Glutaryl-CoA dehydrogenase, mitochondrial

1

6

High-throughput

0.479

High

1393493

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

3

High-throughput

0.479

High

1405634

ELF4
ETS-related transcription factor Elf-4

1

20

High-throughput

0.479

High

1405729

KLF6
Krueppel-like factor 6

1

20

High-throughput

0.479

High

1408323

PKP2
Plakophilin-2

1

20

High-throughput

0.479

High

1415534

GNL3
Guanine nucleotide-binding protein-like 3

1

8

High-throughput

0.479

High

1415862

DDA1
DET1- and DDB1-associated protein 1

1

4

High-throughput

0.479

High

1429934

P63
Tumor protein 63

1

20

High-throughput

0.479

High

1429937

SP110
Sp110 nuclear body protein

1

17

High-throughput

0.479

High

1429940

TPC
Mitochondrial thiamine pyrophosphate carrier

1

9

High-throughput

0.479

High

1429945

GNL3L
Guanine nucleotide-binding protein-like 3-like protein

1

8

High-throughput

0.479

High

1429948

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

7

High-throughput

0.479

High

1429952

KLF15
Krueppel-like factor 15

1

20

High-throughput

0.479

High

1429954

CHIP
E3 ubiquitin-protein ligase CHIP

1

3

High-throughput

0.479

High

1429955

DIM1
Dimethyladenosine transferase

1

1

High-throughput

0.479

High

1429958

CHTOP
Chromatin target of PRMT1 protein

1

1

High-throughput

0.479

High

1429961

MOFA1
MORF4 family-associated protein 1

1

1

High-throughput

0.479

High

1429962

ACL7A
Actin-like protein 7A

1

18

High-throughput

0.479

High

1429963

SQOR
Sulfide:quinone oxidoreductase, mitochondrial

1

2

High-throughput

0.479

High

168121

TIM23
Mitochondrial import inner membrane translocase subunit Tim23

1

0

High-throughput

0.458

High

257571

TI17B
Mitochondrial import inner membrane translocase subunit Tim17-B

1

0

High-throughput

0.458

High

338651

AGRL2
Adhesion G protein-coupled receptor L2

1

0

High-throughput

0.458

High

1244500

IYD1
Iodotyrosine deiodinase 1

1

0

High-throughput

0.458

High

1294958

PALB2
Partner and localizer of BRCA2

1

0

High-throughput

0.458

High

1415765

TIM21
Mitochondrial import inner membrane translocase subunit Tim21

1

0

High-throughput

0.458

High

1429946

BCD1
Box C/D snoRNA protein 1

1

0

High-throughput

0.458

High

911372

IMA5
Importin subunit alpha-5

1

20

High-throughput

0.445

High

1111256

SNW1
SNW domain-containing protein 1

1

4

High-throughput

0.445

High

1367229

ESR2
Estrogen receptor beta

1

20

High-throughput

0.445

High

1429935

LN28A
Protein lin-28 homolog A

1

5

High-throughput

0.445

High

162122

ACOT8
Acyl-coenzyme A thioesterase 8

1

1

High-throughput

0.437

High

337810

SGPL1
Sphingosine-1-phosphate lyase 1

1

3

High-throughput

0.437

High

347311

BAG2
BAG family molecular chaperone regulator 2

1

5

High-throughput

0.437

High

995809

ACTC
Actin, alpha cardiac muscle 1

1

16

High-throughput

0.437

High

1060695

SOS1
Son of sevenless homolog 1

1

4

High-throughput

0.437

High

1124536

MAP7
Ensconsin

1

18

High-throughput

0.437

High

1125054

RCN2
Reticulocalbin-2

1

15

High-throughput

0.437

High

1141924

EEA1
Early endosome antigen 1

1

16

High-throughput

0.437

High

1186309

MA7D1
MAP7 domain-containing protein 1

1

14

High-throughput

0.437

High

1310789

CUL9
Cullin-9

1

7

High-throughput

0.437

High

1311853

DHX40
Probable ATP-dependent RNA helicase DHX40

1

19

High-throughput

0.437

High

1337775

RTL9
Retrotransposon Gag-like protein 9

1

19

High-throughput

0.437

High

1393540

MR1L1
MORF4 family-associated protein 1-like 1

1

1

High-throughput

0.437

High

1395109

TMX3
Protein disulfide-isomerase TMX3

1

11

High-throughput

0.437

High

1411409

CAB45
45 kDa calcium-binding protein

1

14

High-throughput

0.437

High

1428532

DDX24
ATP-dependent RNA helicase DDX24

1

20

High-throughput

0.437

High

1429960

RPGF2
Rap guanine nucleotide exchange factor 2

1

5

High-throughput

0.437

High

1316982

FAM9B
Protein FAM9B

1

0

High-throughput

0.426

High

1256385

E400N
Putative EP400-like protein

1

2

High-throughput

0.407

High

1335713

MOT11
Monocarboxylate transporter 11

1

2

High-throughput

0.407

High

423845

APOD
Apolipoprotein D

1

0

High-throughput

0.279

Low

1351823

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.279

Low

1429939

TM165
Putative divalent cation/proton antiporter TMEM165

1

0

High-throughput

0.249

Low

1405993

C10
Protein C10

1

0

High-throughput

0.232

Low

1429941

RAB18
Ras-related protein Rab-18

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025