HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: FBXW9 (Q5XUX1)
F-box/WD repeat-containing protein 9 (F-box and WD-40 domain-containing protein 9)
Gene: FBXW9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 556 Hs			1 458
+	Hs
		573406 TCPA_HUMAN (1-556): 0: 630: 100.00		FBXW7_HUMAN (28-410): 1.22e-75: 252: 16.03
+	Hs
		826708 TCPG_HUMAN (5-550): 0: 593: 33.03		FBXW9_HUMAN (1-458): 6.68e-92: 287: 100.00
+	Hs
		1140919 TCPH_HUMAN (1-545): 0: 566: 34.84		FBXW9_HUMAN (1-458): 6.68e-92: 287: 100.00
+	Hs
		826807 TCPG_HUMAN (5-550): 0: 593: 33.03		FBXW7_HUMAN (28-410): 1.22e-75: 252: 16.03
+	Hs
		573371 TCPA_HUMAN (1-556): 0: 630: 100.00		POC1A_HUMAN (253-457): 1.77e-48: 172: 12.96
+	Hs
		573384 TCPA_HUMAN (1-556): 0: 630: 100.00		POC1B_HUMAN (253-457): 9.53e-47: 170: 13.89
+	Hs
		826772 TCPG_HUMAN (5-550): 0: 593: 33.03		POC1A_HUMAN (253-457): 1.77e-48: 172: 12.96
+	Hs
		826784 TCPG_HUMAN (5-550): 0: 593: 33.03		POC1B_HUMAN (253-457): 9.53e-47: 170: 13.89
+	Hs
		573342 TCPA_HUMAN (1-556): 0: 630: 100.00		WDR86_HUMAN (167-458): 3.39e-31: 125: 18.41
+	Hs
		573412 TCPA_HUMAN (1-556): 0: 630: 100.00		SNR40_HUMAN (1-248): 1.16e-20: 94.9: 11.83
+	Hs
		826743 TCPG_HUMAN (5-550): 0: 593: 33.03		WDR86_HUMAN (167-458): 3.39e-31: 125: 18.41
+	Hs
		573346 TCPA_HUMAN (1-556): 0: 630: 100.00		WDR5B_HUMAN (372-458): 2.99e-15: 78.4: 17.58
+	Hs
		573201 TCPA_HUMAN (1-556): 0: 630: 100.00		WDR5_HUMAN (35-203): 9.39e-13: 71.1: 10.73
+	Hs
		1198554 TCPH_HUMAN (1-545): 0: 566: 34.84		WDR86_HUMAN (167-458): 3.39e-31: 125: 18.41
+	Hs
		792942 TCPG_HUMAN (5-550): 0: 593: 33.03		LIS1_HUMAN (377-458): 1.64e-16: 83: 18.61
+	Hs
		826748 TCPG_HUMAN (5-550): 0: 593: 33.03		WDR5B_HUMAN (372-458): 2.99e-15: 78.4: 17.58
+	Hs
		826601 TCPG_HUMAN (5-550): 0: 593: 33.03		WDR5_HUMAN (35-203): 9.39e-13: 71.1: 10.73
+	Hs
		826945 TCPG_HUMAN (5-550): 0: 593: 33.03		FBW1A_HUMAN (51-222): 1.02e-11: 69.1: 10.38
+	Hs
		1202777 TCPH_HUMAN (1-545): 0: 566: 34.84		WDR5B_HUMAN (372-458): 2.99e-15: 78.4: 17.58
+	Hs
		903467 TCPH_HUMAN (1-545): 0: 566: 34.84		WDR5_HUMAN (35-203): 9.39e-13: 71.1: 10.73