HitPredict

Interactor 1: HXB2 (P14652)
Homeobox protein Hox-B2 (Homeobox protein Hox-2.8) (Homeobox protein Hox-2H) (K8)
Gene: HOXB2

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35016035
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0007399 - nervous system development GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 356 Hs			1 2414
+	Hs
		725250 TLX1_HUMAN (52-250): 2.57e-41: 149: 25.63		EP300_HUMAN (1-2414): 0: 1100: 100.00
+	Hs
		662220 PAX7_HUMAN (122-339): 1.43e-32: 128: 22.02		EP300_HUMAN (1-2414): 0: 1100: 100.00
+	Hs
		685173 PAX6_HUMAN (88-333): 3.82e-32: 126: 18.25		EP300_HUMAN (1-2414): 0: 1100: 100.00
+	Hs
		725350 TLX1_HUMAN (52-250): 2.57e-41: 149: 25.63		NCOA3_HUMAN (1849-2386): 9.34e-52: 204: 21.89
+	Hs
		662305 PAX7_HUMAN (122-339): 1.43e-32: 128: 22.02		NCOA3_HUMAN (1849-2386): 9.34e-52: 204: 21.89
+	Hs
		574031 HXB2_HUMAN (1-356): 1.42e-64: 210: 100.00		CBP_HUMAN (1876-2412): 3.02e-09: 65.2: 10.52
+	Hs
		214484 HXA2_HUMAN (1-355): 7.58e-59: 196: 47.35		SYNJ1_HUMAN (18-469): 8.66e-10: 66.6: 13.21
+	Hs
		725279 TLX1_HUMAN (52-250): 2.57e-41: 149: 25.63		PB1_HUMAN (1009-1145): 3.36e-12: 74.8: 22.46
+	Hs
		725297 TLX1_HUMAN (52-250): 2.57e-41: 149: 25.63		CBP_HUMAN (1876-2412): 3.02e-09: 65.2: 10.52
+	Hs
		725330 TLX1_HUMAN (52-250): 2.57e-41: 149: 25.63		CHD7_HUMAN (15-365): 3.31e-09: 64.8: 8.05
+	Hs
		724939 HXA10_HUMAN (53-206): 1.69e-39: 146: 36.65		CBP_HUMAN (1876-2412): 3.02e-09: 65.2: 10.52
+	Mm
		107044 HXA9_MOUSE (46-205): 3.78e-36: 133: 34.38		F8VPR5_MOUSE (1752-2401): 1.29e-11: 72.9: 12.77
+	Hs
		685251 PAX6_HUMAN (88-333): 3.82e-32: 126: 18.25		PB1_HUMAN (1009-1145): 3.36e-12: 74.8: 22.46
+	Hs
		725000 HXA9_HUMAN (46-205): 3.64e-36: 133: 34.38		CBP_HUMAN (1876-2412): 3.02e-09: 65.2: 10.52
+	Hs
		662260 PAX7_HUMAN (122-339): 1.43e-32: 128: 22.02		CBP_HUMAN (1876-2412): 3.02e-09: 65.2: 10.52
+	Hs
		662289 PAX7_HUMAN (122-339): 1.43e-32: 128: 22.02		CHD7_HUMAN (15-365): 3.31e-09: 64.8: 8.05
+	Hs
		215905 PAX6_HUMAN (88-333): 3.82e-32: 126: 18.25		SYNJ1_HUMAN (18-469): 8.66e-10: 66.6: 13.21
+	Hs
		685176 PAX6_HUMAN (88-333): 3.82e-32: 126: 18.25		BPTF_HUMAN (1805-2217): 1.15e-09: 66.4: 12.00
+	Hs
		685291 PAX6_HUMAN (88-333): 3.82e-32: 126: 18.25		CBP_HUMAN (1876-2412): 3.02e-09: 65.2: 10.52
+	Hs
		685368 PAX6_HUMAN (88-333): 3.82e-32: 126: 18.25		CHD7_HUMAN (15-365): 3.31e-09: 64.8: 8.05