HitPredict

Interactor 1: PTPRA (P18433)
Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48)
Gene: PTPRA

Interactor 2: GAB1 (Q13480)
GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
Gene: GAB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27880917, 32062451
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008286 - insulin receptor signaling pathway
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 802 Hs			1 694
+	Hs
		617108 PTPRG_HUMAN (14-798): 0: 788: 29.12		GAB1_HUMAN (1-694): 0: 547: 100.00
+	Hs
		1020092 PTPRJ_HUMAN (516-797): 1.76e-118: 390: 38.87		GAB1_HUMAN (1-694): 0: 547: 100.00
+	Hs
		616917 PTPRB_HUMAN (443-796): 5.85e-116: 389: 31.11		GAB1_HUMAN (1-694): 0: 547: 100.00
+	Hs
		1035378 PTPRO_HUMAN (509-789): 1.49e-113: 375: 34.51		GAB1_HUMAN (1-694): 0: 547: 100.00
+	Hs
		796400 PTN9_HUMAN (517-794): 2.95e-117: 368: 38.01		GAB1_HUMAN (1-694): 0: 547: 100.00
+	Hs
		441197 PTPRC_HUMAN (211-516): 1.3e-77: 275: 28.91		GAB1_HUMAN (1-694): 0: 547: 100.00
+	Hs
		665968 PTN6_HUMAN (504-796): 1.16e-112: 357: 32.47		GAB2_HUMAN (3-691): 2.24e-153: 461: 39.01
+	Hs
		665957 PTN6_HUMAN (504-796): 1.16e-112: 357: 32.47		PKHA2_HUMAN (2-210): 3.77e-36: 143: 19.28