HitPredict

Interactor 1: SON (P18583)
Protein SON (Bax antagonist selected in saccharomyces 1) (BASS1) (Negative regulatory element-binding protein) (NRE-binding protein) (Protein DBP-5) (SON3)
Gene: SON

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2426 Hs			1 530
+	Hs
		368952 SON_HUMAN (1-2426): 0: 655: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		487116 SON_HUMAN (1-2426): 0: 655: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		1154059 NIPBL_HUMAN (1309-2215): 1.08e-60: 234: 12.77		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369815 NIPBL_HUMAN (1309-2215): 1.08e-60: 234: 12.77		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		782571 NIPBL_HUMAN (1309-2215): 1.08e-60: 234: 12.77		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		377401 NIPBL_HUMAN (1309-2215): 1.08e-60: 234: 12.77		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		1270066 PCLO_HUMAN (1506-2320): 1.35e-17: 92.7: 7.19		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269444 SCAFB_HUMAN (1309-2042): 9.77e-17: 89.6: 16.07		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1037860 PRP4K_HUMAN (1837-2057): 3.72e-14: 80.7: 21.53		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		311824 TACC2_HUMAN (3-1233): 8.43e-12: 73.4: 9.06		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1221286 RB12B_HUMAN (1805-2051): 1.21e-11: 72.6: 18.75		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1264774 TITIN_HUMAN (735-1660): 9.25e-11: 70.2: 9.62		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		370278 SCAFB_HUMAN (1309-2042): 9.77e-17: 89.6: 16.07		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369549 PRP4K_HUMAN (1837-2057): 3.72e-14: 80.7: 21.53		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370105 TITIN_HUMAN (735-1660): 9.25e-11: 70.2: 9.62		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370824 NCOR2_HUMAN (1181-2323): 1.92e-09: 65.7: 8.84		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		377537 MUC16_HUMAN (82-2305): 2.16e-27: 125: 8.73		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377303 PRP4K_HUMAN (1837-2057): 3.72e-14: 80.7: 21.53		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377539 TITIN_HUMAN (735-1660): 9.25e-11: 70.2: 9.62		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		487522 NIPBL_HUMAN (1309-2215): 1.08e-60: 234: 12.77		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59