Interactor 1: PVR (P15151)
Poliovirus receptor (Nectin-like protein 5) (NECL-5) (CD antigen CD155)
Gene: PVR
Interactor 2: CD226 (Q15762)
CD226 antigen (DNAX accessory molecule 1) (DNAM-1) (CD antigen CD226)
Gene: CD226
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.78 | 1.00 | 0.886 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12913096, 30591568, 21982860, unassigned3799 |
| Identification Methods | pull down, molecular sieving, surface plasmon resonance, protein array, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C2-set_2~V-set, V-set~V-set |
| Common GO terms | GO:0002860 - positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0038023 - signaling receptor activity GO:0042267 - natural killer cell mediated cytotoxicity and 2 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
