HitPredict

Interactor 1: ARF2 (P19146)
ADP-ribosylation factor 2
Gene: ARF2

Interactor 2: GGA1 (Q06336)
ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1)
Gene: GGA1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.800

Property	Details
Experiments	11124697, 12221117
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Arf~GGA_N-GAT
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 181 Sc			1 557
+	Sc
		503143 ARF1_YEAST (1-179): 5.04e-67: 204: 97.21		GGA1_YEAST (1-557): 1.68e-155: 457: 100.00
+	Sc
		580855 ARF2_YEAST (1-181): 1.43e-68: 207: 100.00		GGA2_YEAST (5-557): 4.88e-132: 398: 49.40
+	Sc
		503089 ARF1_YEAST (1-179): 5.04e-67: 204: 97.21		GGA2_YEAST (5-557): 4.88e-132: 398: 49.40
+	Hs
		574772 ARF4_HUMAN (1-180): 4.02e-70: 211: 71.67		GGA2_HUMAN (9-552): 1.76e-123: 377: 18.33
+	Hs
		913174 ARF6_HUMAN (5-179): 2.41e-69: 209: 65.71		GGA2_HUMAN (9-552): 1.76e-123: 377: 18.33
+	Hs
		950574 ARF1_HUMAN (1-180): 1.74e-67: 205: 77.22		GGA2_HUMAN (9-552): 1.76e-123: 377: 18.33
+	Hs
		897415 ARF3_HUMAN (1-180): 4.57e-67: 204: 75.56		GGA2_HUMAN (9-552): 1.76e-123: 377: 18.33
+	Hs
		212615 ARF6_HUMAN (5-179): 2.41e-69: 209: 65.71		AP1G1_HUMAN (42-553): 6.18e-115: 361: 15.02
+	Hs
		212618 ARF1_HUMAN (1-180): 1.74e-67: 205: 77.22		AP1G1_HUMAN (42-553): 6.18e-115: 361: 15.02
+	Hs
		913175 ARF6_HUMAN (5-179): 2.41e-69: 209: 65.71		GGA1_HUMAN (10-552): 1.56e-112: 350: 18.07
+	Hs
		950740 ARF5_HUMAN (1-180): 6.47e-69: 209: 68.89		GGA1_HUMAN (10-552): 1.56e-112: 350: 18.07
+	Hs
		950575 ARF1_HUMAN (1-180): 1.74e-67: 205: 77.22		GGA1_HUMAN (10-552): 1.56e-112: 350: 18.07
+	Hs
		897416 ARF3_HUMAN (1-180): 4.57e-67: 204: 75.56		GGA1_HUMAN (10-552): 1.56e-112: 350: 18.07
+	Hs
		277049 ARF5_HUMAN (1-180): 6.47e-69: 209: 68.89		STAM2_HUMAN (15-461): 1.2e-74: 248: 14.98
+	Rn
		88618 ARF6_RAT (5-179): 2.41e-69: 209: 65.71		D3ZHG8_RAT (321-552): 8.66e-31: 128: 15.70
+	Rn
		88619 ARF1_RAT (1-180): 1.74e-67: 205: 77.22		D3ZHG8_RAT (321-552): 8.66e-31: 128: 15.70
+	Hs
		913149 ARF6_HUMAN (5-179): 2.41e-69: 209: 65.71		GGA3_HUMAN (318-552): 7.92e-29: 123: 15.29
+	Mm
		950589 ARF1_MOUSE (1-180): 1.74e-67: 205: 77.22		GGA3_MOUSE (317-552): 3.29e-30: 127: 15.77
+	Hs
		950568 ARF1_HUMAN (1-180): 1.74e-67: 205: 77.22		GGA3_HUMAN (318-552): 7.92e-29: 123: 15.29
+	Hs
		897409 ARF3_HUMAN (1-180): 4.57e-67: 204: 75.56		GGA3_HUMAN (318-552): 7.92e-29: 123: 15.29