HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (EC 3.6.5.2) (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.875

The method score is based on:

Property Details
Experiments 33961781, 35235311, 36652389, unassigned3799
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~Ras
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
and 23 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 192
Hs

1 192
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Last updated: 11Aug2025