HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (EC 3.6.5.2) (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: PDZ11 (Q5EBL8)
PDZ domain-containing protein 11 (ATPase-interacting PDZ protein) (Plasma membrane calcium ATPase-interacting single-PDZ protein) (PMCA-interacting single-PDZ protein)
Gene: PDZD11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 140
+	Hs
		988419 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		PDZ11_HUMAN (1-140): 2.8e-49: 156: 100.00
+	Hs
		953485 RAC3_HUMAN (1-191): 4.97e-80: 238: 89.01		PDZ11_HUMAN (1-140): 2.8e-49: 156: 100.00
+	Hs
		988336 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		SNTB2_HUMAN (5-139): 8.5e-30: 114: 24.82
+	Hs
		167687 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		LIN7A_HUMAN (39-137): 3.9e-30: 110: 38.61
+	Hs
		581023 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		SNTB2_HUMAN (5-139): 8.5e-30: 114: 24.82
+	Hs
		601271 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		SNTB2_HUMAN (5-139): 8.5e-30: 114: 24.82
+	Hs
		601281 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		SNTB1_HUMAN (22-129): 5.31e-28: 109: 30.09
+	Hs
		953424 RAC3_HUMAN (1-191): 4.97e-80: 238: 89.01		SNTB2_HUMAN (5-139): 8.5e-30: 114: 24.82
+	Hs
		601455 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		GOPC_HUMAN (23-137): 1.54e-27: 107: 29.06
+	Hs
		1015413 RHOG_HUMAN (1-192): 5.1e-79: 235: 70.83		SNTB2_HUMAN (5-139): 8.5e-30: 114: 24.82
+	Hs
		988871 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		USH1C_HUMAN (5-125): 1.15e-21: 91.1: 27.27
+	Hs
		988325 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		DLG1_HUMAN (47-132): 4.29e-18: 81.1: 33.70
+	Mm
		988891 RAC1_MOUSE (1-192): 3.43e-86: 253: 92.19		DLG4_MOUSE (36-130): 1.43e-17: 79.6: 32.67
+	Hs
		581014 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		DLG1_HUMAN (47-132): 4.29e-18: 81.1: 33.70
+	Hs
		601260 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		DLG1_HUMAN (47-132): 4.29e-18: 81.1: 33.70
+	Mm
		1189508 Q3TLP8_MOUSE (1-192): 1.15e-81: 242: 83.41		DLG4_MOUSE (36-130): 1.43e-17: 79.6: 32.67
+	Hs
		601396 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		DLG3_HUMAN (33-118): 1.92e-16: 76.5: 38.04
+	Hs
		953416 RAC3_HUMAN (1-191): 4.97e-80: 238: 89.01		DLG1_HUMAN (47-132): 4.29e-18: 81.1: 33.70
+	Hs
		1015397 RHOG_HUMAN (1-192): 5.1e-79: 235: 70.83		DLG1_HUMAN (47-132): 4.29e-18: 81.1: 33.70
+	Hs
		953602 RAC3_HUMAN (1-191): 4.97e-80: 238: 89.01		DLG3_HUMAN (33-118): 1.92e-16: 76.5: 38.04