Interactor 1: GCN2 (P15442)
eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (General control non-derepressible protein 2) (Serine/threonine-protein kinase GCN2)
Gene: GCN2
Interactor 2: PKH1 (Q03407)
Serine/threonine-protein kinase PKH1 (EC 2.7.11.1) (3-phosphoinositide-dependent protein kinase 1)
Gene: PKH1
Species: Saccharomyces cerevisiae S288C
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 1.00 | 0.747 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22326914 |
| Identification Methods | pull down, affinity chromatography technology, enzymatic study |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~Pkinase |
| Common GO terms | GO:0005524 - ATP binding GO:0005829 - cytosol GO:0035556 - intracellular signal transduction GO:0106310 - protein serine kinase activity |
| Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores 
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Last updated: 11Aug2025