HitPredict

Interactor 1: ERCC3 (P19447)
General transcription and DNA repair factor IIH helicase/translocase subunit XPB (TFIIH subunit XPB) (EC 5.6.2.4) (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA 3'-5' helicase/translocase XPB) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH basal transcription factor complex 89 kDa subunit) (TFIIH 89 kDa subunit) (TFIIH p89) (Xeroderma pigmentosum group B-complementing protein)
Gene: ERCC3

Interactor 2: S10A2 (P29034)
Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2)
Gene: S100A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 782 Hs			1 98
+	Hs
		584547 ERCC3_HUMAN (1-782): 0: 728: 100.00		S100P_HUMAN (4-92): 8.31e-36: 118: 42.70
+	Hs
		584643 ERCC3_HUMAN (1-782): 0: 728: 100.00		CRNN_HUMAN (2-91): 3.38e-30: 113: 25.56
+	Hs
		416348 ERCC3_HUMAN (1-782): 0: 728: 100.00		S10A9_HUMAN (4-98): 1.67e-30: 105: 32.29
+	Hs
		396680 ERCC3_HUMAN (1-782): 0: 728: 100.00		S10A8_HUMAN (2-89): 6.86e-27: 96.1: 29.55
+	Hs
		584538 ERCC3_HUMAN (1-782): 0: 728: 100.00		FILA_HUMAN (2-90): 2.02e-21: 88.7: 25.84
+	Hs
		584618 ERCC3_HUMAN (1-782): 0: 728: 100.00		S1A7A_HUMAN (1-93): 1.04e-22: 85.7: 23.16
+	Hs
		584557 ERCC3_HUMAN (1-782): 0: 728: 100.00		S10A7_HUMAN (1-93): 1.64e-21: 82.6: 22.11
+	Hs
		134113 DDX3X_HUMAN (204-677): 1.56e-104: 337: 11.22		HORN_HUMAN (2-90): 2.84e-32: 119: 28.09
+	Hs
		133841 DDX3X_HUMAN (204-677): 1.56e-104: 337: 11.22		S10A9_HUMAN (4-98): 1.67e-30: 105: 32.29
+	Hs
		134073 DDX3X_HUMAN (204-677): 1.56e-104: 337: 11.22		FILA2_HUMAN (4-91): 2.11e-27: 105: 32.96
+	Hs
		133879 DDX3X_HUMAN (204-677): 1.56e-104: 337: 11.22		FILA_HUMAN (2-90): 2.02e-21: 88.7: 25.84