HitPredict

Interactor 1: MAK11 (P20484)
Protein MAK11 (Maintenance of killer protein 11)
Gene: MAK11

Interactor 2: RRP5 (Q05022)
rRNA biogenesis protein RRP5 (Ribosomal RNA-processing protein 5) (U3 small nucleolar RNA-associated protein RRP5) (U3 snoRNA-associated protein RRP5)
Gene: RRP5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	17308036, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 414 Sc			1 1729
+	Hs
		903230 WDR5_HUMAN (269-411): 1.15e-16: 82.2: 11.11		RRP5_HUMAN (35-1717): 4.59e-129: 448: 15.89
+	Hs
		1058048 NLE1_HUMAN (268-411): 1.73e-15: 79.9: 15.23		RRP5_HUMAN (35-1717): 4.59e-129: 448: 15.89
+	Hs
		1058000 SNR40_HUMAN (282-390): 1.64e-12: 70.3: 14.41		RRP5_HUMAN (35-1717): 4.59e-129: 448: 15.89
+	Hs
		175317 FBW1A_HUMAN (40-381): 1.28e-62: 213: 15.10		OGT1_HUMAN (1295-1728): 5.36e-41: 167: 12.33
+	Hs
		672800 WDR5_HUMAN (269-411): 1.15e-16: 82.2: 11.11		CDC27_HUMAN (1106-1729): 6.38e-66: 243: 12.30
+	Hs
		175177 TBL1R_HUMAN (144-411): 1.18e-40: 152: 12.46		OGT1_HUMAN (1295-1728): 5.36e-41: 167: 12.33
+	Hs
		175294 FBW1B_HUMAN (39-201): 1.65e-25: 110: 22.67		OGT1_HUMAN (1295-1728): 5.36e-41: 167: 12.33
+	Hs
		300222 FBXW7_HUMAN (135-411): 3.75e-47: 173: 13.17		PRP6_HUMAN (1487-1729): 4.01e-19: 96.3: 15.16
+	Hs
		174768 WDR5_HUMAN (269-411): 1.15e-16: 82.2: 11.11		OGT1_HUMAN (1295-1728): 5.36e-41: 167: 12.33
+	Dm
		571971 Q9VPL0_DROME (267-396): 4.65e-11: 65.7: 12.12		CRN_DROME (1245-1728): 7.77e-41: 164: 11.59
+	Hs
		1288293 SNR40_HUMAN (282-390): 1.64e-12: 70.3: 14.41		CRNL1_HUMAN (1208-1729): 7.73e-38: 156: 11.75
+	Sp
		1015545 YIDC_SCHPO (177-411): 2.39e-30: 123: 12.40		PRP1_SCHPO (1310-1729): 3.09e-19: 96.7: 12.77
+	Zm
		29479 A0A1D6KS63_MAIZE (38-181): 3.3e-31: 128: 22.60		A0A1D6K0I4_MAIZE (1559-1711): 6.85e-12: 72.2: 25.49
+	Hs
		196929 PRP4_HUMAN (4-134): 2.82e-20: 94.6: 15.67		PRP6_HUMAN (1487-1729): 4.01e-19: 96.3: 15.16
+	Hs
		300095 WDR5_HUMAN (269-411): 1.15e-16: 82.2: 11.11		PRP6_HUMAN (1487-1729): 4.01e-19: 96.3: 15.16
+	Hs
		300229 SNR40_HUMAN (282-390): 1.64e-12: 70.3: 14.41		PRP6_HUMAN (1487-1729): 4.01e-19: 96.3: 15.16
+	Hs
		1288323 SNR40_HUMAN (282-390): 1.64e-12: 70.3: 14.41		SYF1_HUMAN (1511-1727): 3.02e-18: 93.6: 12.31