HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2647 Hs			1 342
+	Hs
		598140 FLNA_HUMAN (1-2647): 0: 2776: 100.00		RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51
+	Hs
		598083 FLNA_HUMAN (1-2647): 0: 2776: 100.00		RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98
+	Hs
		598268 FLNA_HUMAN (1-2647): 0: 2776: 100.00		SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66
+	Hs
		598040 FLNA_HUMAN (1-2647): 0: 2776: 100.00		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		597996 FLNA_HUMAN (1-2647): 0: 2776: 100.00		LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82
+	Hs
		598345 FLNA_HUMAN (1-2647): 0: 2776: 100.00		NLE1_HUMAN (249-341): 1.44e-21: 97.2: 15.05
+	Hs
		598240 FLNA_HUMAN (1-2647): 0: 2776: 100.00		POC1B_HUMAN (6-194): 2.26e-21: 96.4: 8.40
+	Hs
		598294 FLNA_HUMAN (1-2647): 0: 2776: 100.00		GRWD1_HUMAN (206-342): 9.29e-18: 85.5: 17.61
+	Hs
		598209 FLNA_HUMAN (1-2647): 0: 2776: 100.00		WDR5B_HUMAN (2-148): 2.99e-13: 71.4: 10.74
+	Hs
		261236 FLNB_HUMAN (28-2647): 0: 2710: 69.63		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		903137 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		957556 PGBM_HUMAN (181-1251): 3.53e-32: 140: 12.81		SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66