HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2647 Hs			1 315
+	Hs
		597996 FLNA_HUMAN (1-2647): 0: 2776: 100.00		LIS1_HUMAN (63-312): 8.99e-76: 239: 19.78
+	Hs
		598260 FLNA_HUMAN (1-2647): 0: 2776: 100.00		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		598268 FLNA_HUMAN (1-2647): 0: 2776: 100.00		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		598240 FLNA_HUMAN (1-2647): 0: 2776: 100.00		POC1B_HUMAN (2-181): 1.28e-52: 181: 21.43
+	Hs
		598040 FLNA_HUMAN (1-2647): 0: 2776: 100.00		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		598209 FLNA_HUMAN (1-2647): 0: 2776: 100.00		WDR5B_HUMAN (138-312): 8.72e-50: 170: 22.22
+	Hs
		598345 FLNA_HUMAN (1-2647): 0: 2776: 100.00		NLE1_HUMAN (184-315): 2.98e-35: 134: 22.54
+	Hs
		261236 FLNB_HUMAN (28-2647): 0: 2710: 69.63		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		903137 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		957555 PGBM_HUMAN (181-1251): 3.53e-32: 140: 12.81		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		957556 PGBM_HUMAN (181-1251): 3.53e-32: 140: 12.81		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47