Interactor 1: ISY1 (P21374)
Pre-mRNA-splicing factor ISY1 (Interactor of SYF1) (PRP19-associated complex protein 30)
Gene: ISY1

Interactor 2: SYF1 (Q04048)
Pre-mRNA-splicing factor SYF1 (PRP19-associated complex protein 90) (Synthetic lethal with CDC40 protein 1)
Gene: SYF1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.761

The method score is based on:

Property Details
Experiments 11102353, 11842115, 10688190, 11283351, 16554755, 10094305, 19617314, 37968396, 18719252, 24919400
Identification Methods two hybrid, coimmunoprecipitation, two hybrid pooling approach, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000974 - Prp19 complex
GO:0071006 - U2-type catalytic step 1 spliceosome
GO:0071007 - U2-type catalytic step 2 spliceosome
GO:0071014 - post-mRNA release spliceosomal complex
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 235
Sc

1 859
+ Ce
+ Hs
+ Sc
+ Dm
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024