Protein: AP2A
AP-2 complex subunit alpha (Alpha-adaptin)

Gene: AP2A, AP-2alpha
Organism: Drosophila melanogaster
Interactions: 64
UniProt ID: P91926

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0005905 - clathrin-coated pit
GO:0006886 - intracellular protein transport
GO:0006897 - endocytosis
GO:0008104 - intracellular protein localization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

264393

O62530
Adaptor protein complex 2, mu subunit, isoform A

2

20

High-throughput

0.737

High

1019489

Q24253
AP complex subunit beta

2

16

High-throughput

0.737

High

1019504

Q9VDC3
AP complex subunit sigma

2

20

High-throughput

0.737

High

597772

NUMB
Protein numb

6

20

Small-scale

0.723

High

1019495

Q7KT38
non-specific serine/threonine protein kinase

3

16

Small-scale

0.640

High

95603

E3CTP7
Epidermal growth factor receptor pathway substrate clone 15, isoform D

2

20

Small-scale

0.584

High

1019488

Q0E8K8
FI21816p1

1

12

High-throughput

0.536

High

1019509

Q9VGU4
FI02822p

1

12

High-throughput

0.536

High

56772

KIF1A
Kinesin-like protein unc-104

1

9

Small-scale

0.479

High

118351

M9NDL7
RALBP1 associated Eps domain containing, isoform B

1

20

High-throughput

0.479

High

638690

SY65
Synaptotagmin 1

1

2

Small-scale

0.479

High

753702

FAT
Cadherin-related tumor suppressor

1

2

High-throughput

0.479

High

1019496

Q7KU90
Liquid facets, isoform B

1

20

Small-scale

0.479

High

1019507

Q9VFK5
Aftiphilin, isoform B

1

1

Small-scale

0.479

High

1019534

Q9Y0Y5
Coatomer subunit epsilon

1

1

High-throughput

0.445

High

1019497

Q8INF6
Hexamethylene bisacetamide inducible, isoform B

1

7

High-throughput

0.437

High

1019505

RLIP
RalA-binding protein 1

1

14

High-throughput

0.437

High

1019508

Q9VGI1
FI23955p1

1

1

Small-scale

0.437

High

53116

A1Z7K8
AaRS-interacting multifunctional protein 1

1

2

High-throughput

0.407

High

654843

MA205
205 kDa microtubule-associated protein

1

3

High-throughput

0.407

High

847855

SNRPA
U1 small nuclear ribonucleoprotein A

1

3

High-throughput

0.407

High

925787

SET
Protein SET

1

1

High-throughput

0.407

High

1019490

Q29QQ9
Ribosomal RNA-processing protein 42

1

1

High-throughput

0.407

High

1019491

NUP50
Nuclear pore complex protein Nup50

1

4

High-throughput

0.407

High

1019493

Q7K1Q7
Ribosome assembly factor mrt4

1

2

High-throughput

0.407

High

1019506

Q9VFH2
Hexamethylene bisacetamide inducible, isoform A

1

7

High-throughput

0.407

High

1019510

Q9VGZ2
FI06805p

1

1

High-throughput

0.407

High

1019513

RAGP1
Ran GTPase-activating protein

1

1

High-throughput

0.407

High

1019514

Q9VK19
FI07225p

1

1

High-throughput

0.407

High

1019515

Q9VKW8
U6 snRNA-associated Sm-like protein LSm4

1

1

High-throughput

0.407

High

1019517

Q9VM14
dihydrolipoyllysine-residue acetyltransferase

1

2

High-throughput

0.407

High

1019524

RM39
Large ribosomal subunit protein mL39

1

1

High-throughput

0.407

High

1019528

Q9VZ88
AT07585p

1

3

High-throughput

0.407

High

1019530

Q9W108
FI01540p

1

6

High-throughput

0.407

High

1019533

DDB1
DNA damage-binding protein 1

1

2

High-throughput

0.407

High

1019535

SYQ
Probable glutamine--tRNA ligase

1

2

High-throughput

0.407

High

1019536

Q9Y134
RNA helicase

1

2

High-throughput

0.407

High

1019499

Q8T085
LD21768p

1

0

Small-scale

0.249

Low

1019502

Q9VAD5
LD17744p1

1

0

High-throughput

0.249

Low

1019520

Q9VRD6
NTF2-related export protein

1

0

High-throughput

0.249

Low

54869

A1Z909
LD11307p

1

0

High-throughput

0.232

Low

56821

A1ZAK3
Protein DEK

1

0

High-throughput

0.232

Low

231830

DKC1
H/ACA ribonucleoprotein complex subunit 4

1

0

High-throughput

0.232

Low

718334

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.232

Low

1019492

Q7K0L8
FLICE-associated huge protein, isoform A

1

0

High-throughput

0.232

Low

1019494

DHX15
ATP-dependent RNA helicase DHX15 homolog

1

0

High-throughput

0.232

Low

1019498

EXOS3
Exosome complex component RRP40

1

0

High-throughput

0.232

Low

1019500

NASP
Nuclear autoantigenic sperm protein homolog

1

0

High-throughput

0.232

Low

1019501

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.232

Low

1019503

Q9VC93
Exosome complex exonuclease RRP44

1

0

High-throughput

0.232

Low

1019511

Q9VHT5
Large ribosomal subunit protein uL1m

1

0

High-throughput

0.232

Low

1019512

SMD2
Probable small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.232

Low

1019516

Q9VL60
RE01590p

1

0

High-throughput

0.232

Low

1019518

RM10
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.232

Low

1019519

Q9VPM0
GH06023p

1

0

High-throughput

0.232

Low

1019521

DBR1
Lariat debranching enzyme

1

0

High-throughput

0.232

Low

1019522

QTRT2
Queuine tRNA-ribosyltransferase accessory subunit 2

1

0

High-throughput

0.232

Low

1019523

Q9VT38
GH03795p

1

0

High-throughput

0.232

Low

1019525

RUXG
Probable small nuclear ribonucleoprotein G

1

0

High-throughput

0.232

Low

1019526

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

1019527

Q9VYT3
FI23714p1

1

0

High-throughput

0.232

Low

1019529

THUM1
THUMP domain-containing protein 1 homolog

1

0

High-throughput

0.232

Low

1019531

Q9W1M9
Exosome complex component RRP4

1

0

High-throughput

0.232

Low

1019532

ZN593
Zinc finger protein 593 homolog

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025