HitPredict

Interactor 1: PIWL2 (A2CEI6)
Piwi-like protein 2 (EC 3.1.26.-)
Gene: piwil2

Interactor 2: TDRD5 (Q1L981)
Tudor domain-containing protein 5
Gene: TDRD5

Species: Danio rerio

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21743441
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0071546 - pi-body GO:0141196 - transposable element silencing by piRNA-mediated DNA methylation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1046 Dr			1 905
+	Dr
		60036 PIWL2_DANRE (1-1046): 0: 1269: 100.00		TDRD9_DANRE (198-723): 2.65e-65: 241: 14.95
+	Dr
		60043 PIWL2_DANRE (1-1046): 0: 1269: 100.00		TDRD1_DANRE (400-763): 1.71e-25: 115: 14.48
+	Dr
		60038 PIWL2_DANRE (1-1046): 0: 1269: 100.00		F1QTF8_DANRE (401-650): 9.28e-24: 110: 19.77
+	Dr
		60039 PIWL2_DANRE (1-1046): 0: 1269: 100.00		F1R3C5_DANRE (204-748): 9.51e-19: 94.3: 10.24
+	Hs
		1394719 PIWL1_HUMAN (188-1046): 0: 988: 39.40		TDRKH_HUMAN (256-724): 6.88e-90: 298: 16.35
+	Mm
		1282817 PIWL1_MOUSE (185-1046): 0: 988: 39.38		TDRKH_MOUSE (256-724): 1.33e-86: 289: 16.56
+	Mm
		1260991 PIWL1_MOUSE (185-1046): 0: 988: 39.38		SND1_MOUSE (241-702): 9.04e-78: 273: 15.63
+	Hs
		1270394 PIWL1_HUMAN (188-1046): 0: 988: 39.40		SND1_HUMAN (241-702): 1.29e-77: 273: 15.20
+	Hs
		1277694 PIWL4_HUMAN (175-1046): 0: 910: 34.51		TDRKH_HUMAN (256-724): 6.88e-90: 298: 16.35
+	Rn
		1226832 AGO2_RAT (269-1042): 0: 915: 20.64		SND1_RAT (241-702): 1.85e-77: 273: 15.85
+	Mm
		1298277 PIWL2_MOUSE (107-1046): 0: 1052: 57.16		TDRD1_MOUSE (294-670): 7.61e-31: 133: 13.43
+	Mm
		1408890 PIWL1_MOUSE (185-1046): 0: 988: 39.38		TDRD1_MOUSE (294-670): 7.61e-31: 133: 13.43
+	Ce
		114174 G5EGR6_CAEEL (178-1042): 0: 884: 17.43		Q19328_CAEEL (242-699): 4.29e-43: 171: 11.42
+	Dr
		1201806 PIWL1_DANRE (207-1046): 0: 937: 38.71		TDRD1_DANRE (400-763): 1.71e-25: 115: 14.48
+	Mm
		1298792 AGO2_MOUSE (269-1042): 0: 916: 20.64		TDRD1_MOUSE (294-670): 7.61e-31: 133: 13.43
+	Mm
		1298582 PIWL4_MOUSE (200-1046): 0: 915: 35.91		TDRD1_MOUSE (294-670): 7.61e-31: 133: 13.43
+	Mm
		1298798 AGO1_MOUSE (274-1042): 0: 905: 20.29		TDRD1_MOUSE (294-670): 7.61e-31: 133: 13.43
+	Mm
		1298784 AGO3_MOUSE (271-1042): 0: 873: 19.91		TDRD1_MOUSE (294-670): 7.61e-31: 133: 13.43
+	Mm
		1298782 AGO4_MOUSE (272-1042): 0: 871: 20.00		TDRD1_MOUSE (294-670): 7.61e-31: 133: 13.43
+	Dm
		682701 AGO3_DROME (233-1046): 0: 831: 35.78		TUD_DROME (207-639): 4.13e-17: 89: 14.48