HitPredict

Interactor 1: AGO4 (Q8CJF8)
Protein argonaute-4 (Argonaute4) (mAgo4) (Argonaute RISC catalytic component 4) (Eukaryotic translation initiation factor 2C 4) (eIF-2C 4) (eIF2C 4) (Piwi/argonaute family protein meIF2C4)
Gene: AGO4

Interactor 2: TDRD1 (Q99MV1)
Tudor domain-containing protein 1
Gene: TDRD1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19345100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 861 Mm			1 1172
+	Mm
		1298798 AGO1_MOUSE (8-861): 0: 1159: 82.67		TDRD1_MOUSE (1-1172): 0: 1089: 100.00
+	Mm
		1298792 AGO2_MOUSE (6-861): 0: 1152: 77.58		TDRD1_MOUSE (1-1172): 0: 1089: 100.00
+	Mm
		1298784 AGO3_MOUSE (5-861): 0: 1143: 80.95		TDRD1_MOUSE (1-1172): 0: 1089: 100.00
+	Mm
		1408890 PIWL1_MOUSE (17-828): 0: 736: 22.14		TDRD1_MOUSE (1-1172): 0: 1089: 100.00
+	Mm
		1298582 PIWL4_MOUSE (21-824): 0: 703: 22.59		TDRD1_MOUSE (1-1172): 0: 1089: 100.00
+	Mm
		1298277 PIWL2_MOUSE (22-823): 0: 692: 22.10		TDRD1_MOUSE (1-1172): 0: 1089: 100.00
+	Dr
		1201806 PIWL1_DANRE (10-824): 0: 707: 24.37		TDRD1_DANRE (86-1146): 0: 742: 31.18
+	Hs
		1435701 AGO1_HUMAN (8-861): 0: 1159: 82.67		TDRD3_HUMAN (9-363): 3.8e-53: 200: 16.12
+	Hs
		1435700 AGO2_HUMAN (12-861): 0: 1150: 78.24		TDRD3_HUMAN (9-363): 3.8e-53: 200: 16.12
+	Rn
		1226832 AGO2_RAT (6-861): 0: 1151: 77.47		SND1_RAT (232-441): 6.17e-26: 117: 22.37
+	Ce
		114174 G5EGR6_CAEEL (13-861): 0: 1070: 64.32		Q19328_CAEEL (251-444): 1.01e-27: 123: 18.97
+	Hs
		1394719 PIWL1_HUMAN (17-828): 0: 740: 22.57		TDRKH_HUMAN (445-695): 3.62e-48: 183: 19.31
+	Mm
		1282817 PIWL1_MOUSE (17-828): 0: 736: 22.14		TDRKH_MOUSE (455-693): 1.9e-45: 175: 19.03
+	Hs
		1277694 PIWL4_HUMAN (21-824): 0: 691: 21.61		TDRKH_HUMAN (445-695): 3.62e-48: 183: 19.31
+	Dr
		60039 PIWL2_DANRE (5-823): 0: 688: 20.53		F1R3C5_DANRE (211-671): 2e-42: 172: 21.86
+	Mm
		1260991 PIWL1_MOUSE (17-828): 0: 736: 22.14		SND1_MOUSE (232-441): 1.02e-26: 120: 22.37
+	Hs
		1270394 PIWL1_HUMAN (17-828): 0: 740: 22.57		SND1_HUMAN (232-441): 5.94e-25: 114: 23.29
+	Dr
		60036 PIWL2_DANRE (5-823): 0: 688: 20.53		TDRD9_DANRE (481-711): 1.53e-31: 136: 17.92
+	Dr
		60041 PIWL2_DANRE (5-823): 0: 688: 20.53		TDRD5_DANRE (415-672): 4.17e-31: 134: 20.76
+	Dr
		60038 PIWL2_DANRE (5-823): 0: 688: 20.53		F1QTF8_DANRE (182-412): 7.99e-22: 104: 15.95