HitPredict

Interactor 1: C5AR1 (P21730)
C5a anaphylatoxin chemotactic receptor 1 (C5a anaphylatoxin chemotactic receptor) (C5a-R) (C5aR) (CD antigen CD88)
Gene: C5AR1

Interactor 2: CTR2 (P52569)
Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2)
Gene: SLC7A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 350 Hs			1 658
+	Hs
		626506 FPR2_HUMAN (13-350): 2.59e-83: 258: 32.10		CTR2_HUMAN (1-658): 3.63e-180: 528: 100.00
+	Hs
		854868 CXCR4_HUMAN (6-323): 1.6e-67: 217: 26.24		CTR2_HUMAN (1-658): 3.63e-180: 528: 100.00
+	Hs
		598928 FPR1_HUMAN (13-349): 9.02e-67: 215: 30.57		CTR2_HUMAN (1-658): 3.63e-180: 528: 100.00
+	Hs
		854914 C5AR2_HUMAN (2-339): 6.08e-65: 210: 38.71		CTR2_HUMAN (1-658): 3.63e-180: 528: 100.00
+	Hs
		600811 C5AR1_HUMAN (1-350): 1.33e-76: 240: 100.00		CTR3_HUMAN (2-619): 3.47e-132: 404: 56.45
+	Hs
		208469 OX2R_HUMAN (2-348): 6.87e-67: 218: 15.37		CTR3_HUMAN (2-619): 3.47e-132: 404: 56.45
+	Hs
		854886 C3AR_HUMAN (201-339): 1.11e-18: 88.6: 35.71		CTR2_HUMAN (1-658): 3.63e-180: 528: 100.00
+	Hs
		600813 C5AR1_HUMAN (1-350): 1.33e-76: 240: 100.00		YLAT2_HUMAN (11-487): 1.1e-97: 311: 18.20
+	Hs
		723286 APJ_HUMAN (18-343): 3.3e-69: 222: 24.71		S12A2_HUMAN (3-503): 1.6e-91: 310: 12.38
+	Hs
		1137085 OR2G6_HUMAN (14-326): 9.69e-68: 217: 12.42		S12A4_HUMAN (6-479): 4.85e-91: 307: 11.21
+	Hs
		849636 CCR4_HUMAN (7-343): 7.98e-66: 213: 23.08		S12A5_HUMAN (6-479): 8.05e-91: 307: 11.55