HitPredict

Interactor 1: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	14-3-3~PK_Tyr_Ser-Thr
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 821 Hs			1 246
+	Hs
		601493 FGFR2_HUMAN (1-821): 0: 863: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		507877 FGFR1_HUMAN (1-820): 0: 772: 71.17		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		609187 FGFR3_HUMAN (10-821): 0: 731: 65.69		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		607896 FGFR4_HUMAN (22-810): 0: 684: 55.86		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		674348 UFO_HUMAN (5-818): 3.59e-160: 490: 22.49		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		909605 NTRK3_HUMAN (166-765): 7.85e-160: 488: 25.31		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		674386 UFO_HUMAN (5-818): 3.59e-160: 490: 22.49		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		683275 ROR2_HUMAN (11-820): 1.91e-156: 482: 20.29		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		926941 ROR2_HUMAN (11-820): 1.91e-156: 482: 20.29		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		384604 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		384357 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		646811 ROR2_HUMAN (11-820): 1.91e-156: 482: 20.29		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		384623 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		384306 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		904454 ROR2_HUMAN (11-820): 1.91e-156: 482: 20.29		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		968362 ROR2_HUMAN (11-820): 1.91e-156: 482: 20.29		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		684060 NTRK3_HUMAN (166-765): 7.85e-160: 488: 25.31		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		683973 ROR2_HUMAN (11-820): 1.91e-156: 482: 20.29		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		384598 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		384358 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62