Protein: IQEC2
IQ motif and SEC7 domain-containing protein 2

Gene: IQEC2, IQSEC2
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q5JU85

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0030036 - actin cytoskeleton organization
GO:0032012 - regulation of ARF protein signal transduction
GO:0050804 - modulation of chemical synaptic transmission

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

516344

CALM1
Calmodulin-1

2

1

Small-scale

0.737

High

1207205

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

8

High-throughput

0.665

High

1207206

APBA2
Amyloid-beta A4 precursor protein-binding family A member 2

3

7

High-throughput

0.662

High

966415

1433G
14-3-3 protein gamma

2

20

High-throughput

0.628

High

516526

CALM3
Calmodulin-3

1

1

High-throughput

0.575

High

938105

ANM2
Protein arginine N-methyltransferase 2

1

6

High-throughput

0.541

High

691077

1433T
14-3-3 protein theta

1

20

High-throughput

0.536

High

729901

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

971604

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.536

High

990307

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

1049369

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

106069

APRIO
Alternative prion protein

2

3

High-throughput

0.533

High

1116814

AVR2B
Activin receptor type-2B

1

0

High-throughput

0.513

High

1091513

DLG1
Disks large homolog 1

1

6

High-throughput

0.501

High

1178828

CF184
Cilia- and flagella-associated protein 184

1

1

High-throughput

0.489

High

791440

SYUA
Alpha-synuclein

1

5

High-throughput

0.481

High

172903

XPO1
Exportin-1

1

3

High-throughput

0.479

High

241904

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

537293

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

978062

RHOB
Rho-related GTP-binding protein RhoB

1

11

High-throughput

0.479

High

988422

RAC1
Ras-related C3 botulinum toxin substrate 1

1

10

High-throughput

0.479

High

1004666

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

1207204

RN123
E3 ubiquitin-protein ligase RNF123

1

2

High-throughput

0.479

High

1207209

HDAC6
Protein deacetylase HDAC6

1

2

High-throughput

0.479

High

1207210

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1207212

XPO7
Exportin-7

1

3

High-throughput

0.479

High

1207207

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

1207211

BI2L1
BAR/IMD domain-containing adapter protein 2-like 1

1

3

Small-scale

0.457

High

1207213

STX8
Syntaxin-8

1

5

High-throughput

0.437

High

255059

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.407

High

888460

TSP3
Thrombospondin-3

3

0

High-throughput

0.347

High

1128632

ZN460
Zinc finger protein 460

1

0

High-throughput

0.279

Low

1207208

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

0

High-throughput

0.279

Low

567880

PRG2
Bone marrow proteoglycan

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025