HitPredict

Interactor 1: TGM2 (P21981)
Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (Isopeptidase TGM2) (EC 3.4.-.-) (Protein-glutamine deamidase TGM2) (EC 3.5.1.44) (Protein-glutamine dopaminyltransferase TGM2) (EC 2.3.1.-) (Protein-glutamine histaminyltransferase TGM2) (EC 2.3.1.-) (Protein-glutamine noradrenalinyltransferase TGM2) (EC 2.3.1.-) (Protein-glutamine serotonyltransferase TGM2) (EC 2.3.1.-) (Tissue transglutaminase) (tTG) (Transglutaminase II) (TGase II) (Transglutaminase-2) (TG2) (TGase-2) (TGase2)
Gene: TGM2

Interactor 2: FNDC5 (Q8K4Z2)
Fibronectin type III domain-containing protein 5 (Fibronectin type III repeat-containing protein 2) (Peroxisomal protein) (PeP) [Cleaved into: Irisin]
Gene: FNDC5

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30550785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005783 - endoplasmic reticulum GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 686 Mm			1 209
+	Mm
		994039 TGM3_MOUSE (4-684): 0: 977: 38.27		FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00
+	Hs
		993977 TGM3_HUMAN (4-684): 0: 962: 38.13		FNDC5_HUMAN (2-209): 4.81e-142: 396: 97.62
+	Mm
		1206514 F13A_MOUSE (2-683): 0: 888: 37.09		FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00
+	Hs
		611288 TGM1_HUMAN (2-686): 0: 896: 36.06		FNDC5_HUMAN (2-209): 4.81e-142: 396: 97.62